Development and reexamination of the dentin adhesion system

本研究的目的是澄清实验性牙科注射剂对33种氨基酸衍生物的影响，并在牙科注射剂的情况下添加到粘合剂中，和债券机制.在被A-primer积极地治疗后，他们添加了18种0.5摩尔%的脂性氨基酸和15种0.5摩尔%的芳香性氨基酸到6重量%的15种0.5摩尔%的脂性氨基酸HEMA水解决方案适当地，B-或C-引物添加了10wt%4-甲基丙烯酸甲酯三聚氰胺（4-MHTA）或10wt%4-甲基丙烯酸甲酯三聚氰胺（4-MDTA），其中适当地合成为A-引物，含有5重量% 4-MHTA或5重量% 4-MDTA适当地应用于牙医，然后，一张照片聚合物类型复合树脂被填充到牙科中，99种牙科粘合剂系统的剪切键强度被测试并与99种引物中的剪切键强度进行了比较，随后的结果被发现。B级引物的剪切键强度被发现是 ... More 显示，A-primer在鉴定的氨基酸中高于A-primer，其价值超过了大约1.5次。另一只手，C级引物的剪切强度比B级引物在同一氨基酸中的价值高出约1.1次。在C级引物的牙科粘合剂系统中，有五种芳香族氨基酸和八种芳香族氨基酸，它们显示出的粘合剂强度约为20兆帕和高价值。在两种4-MHTA和4-MDTA的合成中，甲基链中的4-MDTA很长，而粘合剂强度是成为更高的趋势。此外，如果它将5-wt %的可释放填充物添加到实验绑定代理中，这被认为是由于具有高剪切键强度（COO-）的Dentin粘合剂系统的粘合机制（D22）的高剪切键强度（D2组的4个MDTA形成了稳定键到Ca-D22 + D2 hydroxyapatite and hydrogen bond to the amino group of the collagen in the dentin as ligand monomer in water。Less（低）

The purpose of this study is to clarify the effect of the experimental dentin primers with 33 kinds of amino acid derivatives and to have added into the bonding agents in case of dentin adhesion, and the bond mechanism.After treating to dentins respectively by the A-primers which added 18 kinds of 0.5mol% aliphatic amino acids and 15 kinds of 0.5mol% aromatic amino acid to 6Owt%HEMA water solution respectively, and B- or C-primers which added 10 wt%4-methacryloxydecyl trimellitic anhydride(4-MHTA) or 10 wt%4-methacryloxydecyl trimellitic anhydride (4-MDTA) which was synthesized respectively, to the A-primer, the bonding agent containing 5 wt% 4-MHTA or 5 wt% 4-MDTA respectively was applied to the dentin, and then a photo polymerization-type composite resin was filled to the dentin.The shear bond strength of the 99 kinds of dentin adhesion systems were examined and compared with the 99 kinds of primers, and the following results were obtained.The shear bond strength of the B-primer was … More showed higher than the A-primer in the identical amino acid, and the value was more than about 1.5 times. The other hand, the shear bond strength of the C-primer was more than about 1.1 times as high value the B-primer in the same ammo acid. In the dentin adhesion system of the C-primer, there were five kinds of aromatic amino acids and eight kinds of the aliphatic amino acids that the bond strength showed about 20 Mpa and a high value.In two kinds of 4-MHTA and 4-MDTA which synthesized, 4-MDTA in that the methylene chain is long, the bond strength was the tendency which becomes higher. Also, even if it added 5-wt% fluoric releasable filler into the experimental bonding agent, the bond strength didn't decrease.It was suggested as for the bond mechanism of the dentin adhesion system with high shear bond strength that (COO-)ィイD22ィエD2 group of 4MDTA was formed the chelate bond to CaィイD22+ィエD2 hydroxyapatite and hydrogen bond to the amino group of the collagen in the dentin as ligand monomer in water. Less