Electrochemical synthesis of biocompatible calcium phosphate film and its application on dental implant

本论文研究了电化学沉积生物活性层对生物复合材料表面的改性。在平成5中，研究了模拟体液中磷酸钙在钛上的电化学沉积。给出了电化学沉积低结晶度、不含其他晶相的磷灰石磷酸钙的适宜条件。在平成6号中，重点研究了电化学沉积形成针状磷灰石晶体。根据平成5号的实验结果，得出了针状磷灰石涂层形成的适宜条件。研究了电化学法制备的针状磷灰石涂层对HA-G-Ti复合材料生物活性的影响。本研究表明，在种植初期，复合材料上针状磷灰石和钛的形成可以促进新骨的形成。

The present thesis deals with the surface modification by the electrochemical deposition of bioactive layr on the composite designed for biological application. In Heisei 5, the electrochemical deposition of calcium phosphate on titanium in simulated body fluid was studied. The suitable condition for the electrochemical deposition of the calcium phosphate, which is apatite having low crystallinity and containing no other crystal phase, was given. In Heisei 6, the formation of needle-like apatite crystal by electrochemical depositionwas focused in the research. The suitable condition for the formation of needle-like apatite coating was derived from the experimental results in Heisei 5. The effect of the needle-like apatite coating formed by the electrochemical method on the biological activities of the HA-G-Ti composite was confirmed. The present study demonstrated that the formation of needle-like apatite on the composite and titanium can promote the new bone formation in the early stages of implantation.