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Studies on developmental and manifold applications of diagnostic ultrasound.

诊断超声的发展和多种应用的研究。

基本信息

批准号：
06454127
负责人：
HASHIMOTO Akira
金额：
$ 4.22万
依托单位：
HOKKAIDO UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1994
资助国家：
日本
起止时间：
1994 至 1995
项目状态：
已结题

项目摘要

Results obtained from the present research can be summarized as follows :1. Clinical applications of endoscopic ultrasonography (EUS) in small animal medicine.EUS examinations were done on abdominal viscera in normal dogs and on Caerulein-induced acute pancreatitis and hematoma and cystic lesions in the gastric wall experimentally prepared. It was suggested that EUS was highly useful to image the digestive tract, gall bladder and pancreas. The results obtained from experimental study, suggest that EUS provides useful information especially on pancreatic disease and focal lesions in the digestive tract. Therefore, it is concluded that EUS is an effective diagnostic procedure for small animal practice.2. Application of ultrasound-guided biopsy techniques.On the experimental studies of steroid-induced hepatopathy, Puromycin-induced renal damage and experimental fatty liver in cat and pathobiological changes of the prostate for collection of prostatic fluid, ultrasound-guided biopsy was do … More ne for collection of the liver, kidney and prostatic specimens, respectively. From the results of these experiments, it is demonstrated that ultrasound-guided biopsy is useful, safety and accurate procedure for collection of tissue specimens in small animal medicine.3. Application of the US for the research procedure of experimental animals.The results of serial US examination of Cephaloridine-induced renal lesions suggest that US examination is useful for evaluation of drug-induced nephrotoxicity. The results of US examination of parasitic cysts of the liver infected with Taenia taeniaeformis suggest that US examination is useful for the diagnosis of rat liver parasitic cysts like hydatid as well as following-up development of metacestodes in the liver. These results strongly suggest that US investigation is useful as a effective analytical procedure of the research of experimental animals.4. Application of ultrasound in diagnosis of neoplasia of small animals.Ultrasonographic findings were obtained from various kind of tumor by US examination. Usefulness of color-doppler ultrasound and ultrasound-guided biopsy are also evaluated for detailed and definite diagnosis of the neoplasia.As a conclusion, the results of the present research may become useful information for development of veterinary diagnostic imaging. Less

本文的研究结果可以总结为：1。超声内镜在小动物医学中的临床应用。对正常犬腹部脏器及实验制备的小毛蛋白诱导的急性胰腺炎和胃壁血肿、囊性病变进行EUS检查。提示EUS对消化道、胆囊和胰腺的显像有很高的价值。实验研究结果表明，EUS提供了有用的信息，特别是对胰腺疾病和消化道局灶性病变。因此，EUS是一种有效的小动物手术诊断方法。超声引导活检技术的应用。针对猫的类固醇性肝病、嘌呤霉素性肾损害和实验性脂肪肝的实验研究，以及前列腺液采集时前列腺的病理变化，分别对肝脏、肾脏和前列腺标本进行了超声引导活检。实验结果表明，超声引导下的组织活检是一种有效、安全、准确的小动物组织标本采集方法。美国对实验动物研究程序的应用。头孢立定致肾损害的连续超声检查结果提示超声检查可用于评价药物性肾毒性。对感染带绦虫的肝寄生囊肿进行US检查，提示US检查对大鼠肝包虫病等寄生虫囊肿的诊断以及肝内介壳绦虫的后续发展有一定的指导意义。这些结果强烈地表明，美国调查作为一种有效的实验动物研究分析程序是有用的。超声在小动物肿瘤诊断中的应用。超声检查可获得不同类型肿瘤的超声表现。彩色多普勒超声和超声引导下的活检对肿瘤的详细和明确诊断也有价值。本研究结果可为兽医影像诊断技术的发展提供参考。少