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Studies on the effects of malnutrition during raising stage on the bone growth of calves at subsequent stage

饲养期营养不良对犊牛后期骨骼生长影响的研究

基本信息

批准号：
59480079
负责人：
KAWASHIMA Ryoji
金额：
$ 4.03万
依托单位：
Kyoto University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (B)
财政年份：
1984
资助国家：
日本
起止时间：
1984 至 1986
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-59480079/
关键词：
Calf raising Bone growth,Malnutrition

项目摘要

This study was to investigate the effects of malnutrition during raising sttage on bone growth of calves at subsequent stage. Principal results were as follows:1. Relationships betwwn bone growth and blood constitutents were examined to find the estimation method of the degree of bone growth of living animal without killing. It was concluded that the estimation of bone growth by blood constituents of living animal was very difficult, while there were some correlations between bone growth and calcium or thyroxine levels in blood.2. The method to estimate the bone growth directly in living animal was examined. Morphological growth of bone was estimated by X ray examination, but microdensitometer was necessary to measure the bone density. X ray apparatus and mirodensitometer for human diagnosis was too small for calves, but was useful to estimate the bone growth of lamgs.3. Malnutrition on raising stage of lambs depressed the growth of bone length and bone width. These effects continued for long time even though feed was changed to normal nutritional level. Pregnancy and delivery also depressed the bone growth. Bone density was higher on malnutritional condition than normal condition. of lambs, and was not affected by pregnancy and delivery.4. Blood thyroxine level was depressed by malnutrition in calves and rats. Injection of thyroxine to malnutrition rats did not affect to bone growth. It was suggested that depression of bone growth by malnutrition was not depended only by the thyroxine deficiency.

本研究旨在探讨犊牛饲养阶段营养不良对后期骨骼生长的影响。主要结果如下：1.探讨了骨生长与血液成分之间的关系，以寻求不经屠宰活体动物骨生长程度的估计方法。结论：1.用活体动物血液成分来评价骨生长是非常困难的，而骨生长与血钙、甲状腺素水平之间存在一定的相关性.探讨了直接估算活体动物骨生长的方法。X线检查评价骨形态学生长，骨密度测定需使用显微密度计。X线诊断仪和显微光密度仪对犊牛的诊断偏小，但对羔羊的骨生长有一定的诊断价值.羔羊生长期营养不良抑制了骨长、骨宽的生长。即使将饲料改为正常营养水平，这些影响仍持续很长时间。怀孕和分娩也会抑制骨骼生长。营养不良组骨密度高于正常组。的羔羊，并不受怀孕和分娩.犊牛和大鼠的血液甲状腺素水平因营养不良而降低。营养不良大鼠注射甲状腺素对骨生长无影响。提示营养不良对骨生长发育的抑制作用并非仅依赖于甲状腺素缺乏。