Behavior-genetical. physio-biochemical. and ecological study on the genesis of individual differences in behavior.

本研究的目的是确定个体行为差异产生的原因和过程。行为--遗传。生理生化。并利用筑波大学筛选出的高情绪反应性和低情绪反应性近交系大鼠，对上述问题进行了生态学研究。筑波Emotinal品系(The和TLE)及其衍生的四个杂交品种(F1、F2、B1、B2)在跑道上测试了它们的情绪性。从移动中得到的数据。排便等行为指标采用孟德尔交叉分析。在所有的行为测量中都检测到了加性效应。在男性中发现了对较少情绪性的定向优势，而在女性中则没有。表明情绪性的三种行为指标之间存在遗传相关性。计算遗传力和相关基因座个数。检查筑波情绪紧张是否与选择相关联的…儿茶酚胺、选择素及其代谢物存在或不存在大脑区域含量的差异更大。两株菌在肾上腺素、去甲肾上腺素、多巴胺、血清素、5-羟基吲哚乙酸、3，4-二羟基苯乙酸和3-甲氧基三甲胺等方面存在显著差异。筑波Emotinal菌株在有遮蔽物的开阔场地、有两个末端隔间的直线跑道和I-迷宫中的行为明显不同。在囤积行为、挖掘行为和攻击行为上也检测到了品系差异。对筑波情绪品系进行了味觉厌恶条件反射，其中氯化钠的味道伴随着注射氯化锂引发的疾病。两个菌株在一次试验后都获得了厌恶味觉的条件反射，并保持了四天。然而，TLE希望味道厌恶的速度比THE快。在跑道、空地上对大鼠和小鼠的行为测量。并用主成分分析方法对一个I-迷宫进行了分析。两个品系在半自然条件下繁殖三年的种群大小可能与雄虫的性行为特征有关。较少

The object of this study is to determine the causes and the processes of the genesis of indvivdual differences in behavior. Behavior-genetical. Physio-biochemical. and ecological studies on these problems were performed by using of two inbred strains of rats which had been selected for high and lowemotional reactivity in university of Tsukuba.1. Tsukuba Emotinal Strains (THE and TLE) and their derived four hybrids (F1, F2, B1, B2) were tested for their emotionality in a runway. The resulting data from ambulation. Defecation and other behavioral measures were subjected to the Mendelian cross analysis. Additive effects were detected in all behavioral measures. Directional dominance toward less emotionality was detected in male, wheres in female dominance was absent. Genetic correlations among three behavioral measures which indicated emotionality were found. Heritability and the number of locus related were estimated.2. Tsukuba Emotional Strains were examined whether selection-assoslated … More differences in brain regional contents of catecholamines, seletonin, and their metabolltes exit or not. Two strains significantly differed with regard to adrenaline, noradrenaline, dopamine, seretonin, 5-hydroxyinodoleacetic acid, 3,4-dihydroxyphenylacetic acid, and 3-methoxytryramine.3. Tsukuba Emotinal Strains were significantly different on their behaviors in an openfield with shelter, a straight runway with two end-compartments, and an i-mazy. Strain differences of hoarding behavior, digging behavior, and aggressive behavior were also detected between THE and TLE.4. The taste-aversion conditioning in which taste of NaCl was paired with an illness induced by an injection of lithium chloride was conducted on Tsukuba Emotional Strains. Both strains acquired taste aversion conditioning after one trial, and they retained this for four days. TLE, however, extingwished the taste aversion faster than THE.5. Behavioral measures of rats and mice in a runway, an openfield. and an i-maze were analyzed by the mothod of principal component analysis.6. Population size of both strains bred in a seminatural field for three years would be related to the characteristics of male's sexual behavior. Less