CONTROL OF THYROID HORMONE SECRETION IN SALMONIDS

鲑鱼甲状腺激素分泌的控制

• 批准号: 62480022
• 负责人: HIRANO Tetsuya
• 金额: $ 3.84万
• 依托单位: The University of Tokyo
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1987
• 资助国家: 日本
• 起止时间: 1987 至 1989
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-62480022/
• 关键词: Salmon; Trout; Thyroid Gland; Thyroid Hormones; Thyroxine; Triiodothyronine; Migration; Early Development; ビワマス; ヒラメ; コルチソル; 甲状腺刺激ホルモン

Thyroid hormones have been implicated in migration of salmonids, particularly in their downstream migration associated with smoltification. In this study, a method has been established to extract thyroid hormones, thyroxine and triiodothyronine, from the.egg and whole embryo and to quantify by radioimmunoassays. Thyroid hormones were contained in the yolk of unfertilized eggs of not only salmonids but also of all teleost species so far examined. In chum salmon and rainbow trout, the hormone concentrations decreased gradually until hatching, and then rapidly during yolk absorption.The tissue and plasma levels of the hormones increased during emergence of chum salmon fry from the gravel bed, just before downstream migration.No such increase was seen in non-migratory rainbow trout. A significant increase in the plasma levels of thyroxine was observed in the chum salmon fry as well as in amago salmon during downstream migration. A marked increase in the tissue levels of the thyroid hormones was also observed during metamorphic climax of the flounder larvae. Corticosteroid, cortisol, was also contained ih the salmon eggs, and changes in its concentrations were more or less in parallel with those in the thyroid hormones. The hormones seem to play important roles during early development of fishes, especially in association with migration and metamorphosis.

甲状腺激素与鲑鱼的迁移有关，特别是与银化相关的下游迁移。本研究建立了一种从鸡蛋和全胚胎中提取甲状腺激素甲状腺素和三碘甲腺原氨酸并用放射免疫测定法定量的方法。甲状腺激素包含在蛋黄中的未受精卵不仅鲑鱼，但也所有硬骨鱼种迄今为止检查。在大麻哈鱼和虹鳟鱼中，激素浓度在孵化前逐渐下降，然后在蛋黄吸收期间迅速下降。大麻哈鱼鱼苗从砾石床中出现时，即下游洄游之前，组织和血浆中的激素水平升高。在非洄游性虹鳟鱼中没有观察到这种增加。甲状腺素的血浆水平显着增加，观察到在鲑鱼鱼苗以及在amago鲑鱼在下游迁移。甲状腺激素的组织水平显着增加，也观察到在变性高潮的比目鱼幼虫。鲑鱼卵中也含有皮质类固醇，皮质醇，其浓度的变化或多或少与甲状腺激素的变化平行。这些激素在鱼类早期发育过程中起着重要作用，特别是与洄游和变态有关。

项目成果

Iwata,M.;et al.: Aquaculture.

Iwata,M.；等人：水产养殖。

Tagawa,M.;et al: General and Comparative Endocrinology.

Takawa，M.；等人：普通和比较内分泌学。

Tagawa,S.;T.Hirano: Proc.1st Congr.Asia Oceania Soc.Comp.Endocr.1. 345-346 (1987)

Takawa,S.；T.Hirano：Proc.1st Congr.Asia Oceania Soc.Comp.Endocr.1。

Iwata,M.et al.: "Inocorsistent effect of thyroid hormone alteration on seawater adaptability of fry of chum salmon,Oncorhynchus keta." Nippon Suisan Gakkaishi. 53. 1969-1973 (1987)

Iwata,M.等人：“甲状腺激素改变对大马哈鱼鱼苗海水适应性的不一致影响。”

Hasegawa,S.etal.: Fish Physiology and Biochemistry. 4. 101-110 (1987)

长谷川，S.etal.：鱼类生理学和生物化学。