Studies on metabolism of parathyroid hormone

甲状旁腺激素代谢研究

• 批准号: 62480344
• 负责人: KOHRI Kenjiro
• 金额: $ 2.56万
• 依托单位: Kinki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1987
• 资助国家: 日本
• 起止时间: 1987 至 1989
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-62480344/
• 关键词: hyperparathyroidism; parathyroid hormone; immunostain; フロ-サイトメトリ-; 細胞周期; P H;抗PTH抗体; 副甲状腺ホルモン(PTH)

Hyperfunctioning parathyroids were studied immuno histochemically by Using anti parathyroid hormone antibody.In light microscopic study, immunostaining of the parathyroid could be divided into 4 major types. Type A is that in which cells with staining of the nucleus and cytoplasm were sporadically observed. Type B is that in which the cytoplasm of internal cells in the gland structure was stained. Type C is that in which no portion of the parathyroid was stained satisfactorily. Type D is that in which the cytoplasm of large cells was stained densely and uniformly. In electron microscopic study, only secretory granules were stained specifically.

用抗甲状旁腺激素抗体对甲状旁腺功能亢进进行免疫组化研究，光镜下甲状旁腺免疫染色可分为4种主要类型。A型是偶尔观察到细胞核和细胞质染色的细胞。B型是腺体结构中内部细胞的细胞质被染色的类型。C型是甲状旁腺的任何部分都不能满意地染色。D型是大细胞的胞质染色致密而均匀。电镜下仅分泌颗粒被特异性染色。

项目成果

Kenjiro Kohri et al.: "Calcium oxalate crystal formation in patients with hyperparathyroidism and hyperthyroidism and related metabolic disturbances" Bone and Mineral Vol. 8, 1990, 59-67.

Kenjiro Kohri 等人：“甲状旁腺功能亢进症和甲状腺功能亢进症及相关代谢紊乱患者的草酸钙晶体形成”《骨与矿物质》卷。

Kenjiro Kohri et al.: "Parathyroid hormone and electrolytes during long term treatment with allopurinol and thiazide" Br. J. Urol. Vol. 59, 1987, 503-507.

Kenjiro Kohri 等人：“长期使用别嘌呤醇和噻嗪类药物治疗期间的甲状旁腺激素和电解质”Br。

高田昌彦: 日本泌尿器科学会雑誌.

高田正彦：日本泌尿外科协会杂志。

Kenjiro Kohri et al.: "Calcium oxalate crystal formation in patients with hyperparathyroidism and hyperthyroidism and related metabolic disturbances" Bone and Mineral. 8. 59-67 (1990)

Kenjiro Kohri 等人：“甲状旁腺功能亢进症和甲状腺功能亢进症及相关代谢紊乱患者的草酸钙晶体形成”《骨与矿物质》。

Kiyonori Kataoka et al.: "Urolithiasis "Calcium-oxalate crystal formation in urolithiasis"" Plenum Publishing Corporation 1989, 3.

Kiyonori Kataoka 等人：“尿石症“尿石症中草酸钙晶体的形成””Plenum Publishing Corporation 1989，3。