Tissue Changes Around Single-crystal Sapphire Implant Following Plaque Accumulation.

牙菌斑堆积后单晶蓝宝石植入物周围的组织变化。

• 批准号: 62480390
• 负责人: TSURU Hiromichi
• 金额: $ 3.78万
• 依托单位: HIROSHIMA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (B)
• 财政年份: 1987
• 资助国家: 日本
• 起止时间: 1987 至 1988
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-62480390/
• 关键词: Implant; Morbidly state of implant around tissue; プラーク付着; プラーク

The purpose of this study was to evaluate clinical and histological changes of peri-implant tissuse associated with plaque accumulation. Two single-crystal sapphire implants were inserted into the mandibular edentulous area and the super-structure was set 1 month postinsertion in each of 9 monkeys. Plaque was allowed to accumulate at one side by placing ligature around the implant and natural teeth without plaque control and at the other side plaque controlwas continued for 9 months. Both of the implant and natural teeth with plaque accumulation showed increase in clinical parameters. Histologically, various degrees of inflammatory reaction were seen in the gingiva, but bone-implant interface was intact. On the other hand, the implant and teeth with plaque control showed low values in clinical parameters. Inflammation was scarcely seen in the tissue around implant and natural teeth.These findings demonstrate that plaque control in essential for maintaining health of peri-implant tissuse and suggest that peri-implant gingiva possesses simolar barrier properties against microbial invasion to those of the inherent gingiva.

本研究的目的是评估与斑块积累相关的种植体周围组织的临床和组织学变化。将两个单晶蓝宝石种植体植入 9 只猴子的下颌无牙颌区域，并在植入后 1 个月设置上部结构。通过在种植体和天然牙周围放置结扎线，使牙菌斑积聚在一侧，而无需进行牙菌斑控制，而另一侧的牙菌斑控制持续 9 个月。具有牙菌斑积聚的种植牙和天然牙均显示出临床参数的增加。组织学上，牙龈处可见不同程度的炎症反应，但骨-种植体界面完好。另一方面，具有牙菌斑控制的种植体和牙齿的临床参数值较低。种植体和天然牙周围的组织几乎没有出现炎症。这些发现表明，牙菌斑控制对于维持种植体周围组织的健康至关重要，并表明种植体周围牙龈具有与固有牙龈类似的屏障特性，可以防止微生物入侵。

项目成果

津留宏道,橋本正毅,赤川安正,松本仁門,二階宏昌: "オーラル・マキシロフェイシャル・インプラント「術後のケアを考えたサニタリー」" クインテッセンス出版, 147-156 (1987)

Hiromichi Tsuru、Masatake Hashimoto、Yasumasa Akakawa、Jinmon Matsumoto、Hiromasa Nikai：《口腔颌面种植体“考虑术后护理的卫生》Quintessence Publishing，147-156（1987）

Hiromichi,Tsuru; Masaki,Hashimoto; Yasumasa,Akagawa; Toshikado,Matsumoto; Hiromasa,Nikai: Sanitary Care of After Treatment. Quintessence, 147-156 (1987)

弘道，鹤；