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In vivo measurement of temperature dependent permittivity of tissues in asmall region

小区域组织温度依赖性介电常数的体内测量

基本信息

批准号：
04650367
负责人：
MIYAKAWA Michio
金额：
$ 1.34万
依托单位：
Niigata University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1992
资助国家：
日本
起止时间：
1992 至 1993
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-04650367/
关键词：
tissue permittivity temperature dependence in vivo measurement small region microwave region coaxial probe reflection method tissue heating マイクロ波帯 RF帯

项目摘要

A new method for measuring the temperature dependence of tissue permittivity in the small region has been developed by use of the small coaxial probe, vector network analyzer, and RF power source. The developed coaxial probe is used not only for permittivity measurement but also for increasing temperature in the small region of measurement. Temperature coefficients of the permittivity are calculated from complex permittivity measured at different temperatures. Throughout the research, we have obtained the following results.1. Region of the measurement by the coaxial probe has been clarified.2. The coaxial probe equipped with four small temperature sensors has been developed for permittivity measurement and heat generation in the small region of interest.3. The measuring method of the temperature distribution under the coaxial probe has been developed.4.We have proposed a method to estimate the average temperature change in the region of measurement.5.The estimated temperature coefficients show a good agreement with temperature coefficients of complex permittivity of the phantom model of simulated tissues obtained by the other method.In conclusion, we have developed the method for in vivo measurement of temperature coefficient of the tissue permittivity. The method can practically be used for measuring temperature dependent permittivity of various tissues. Information on the temperature dependence is utilized for non-invasive temperature mapping by the microwave computed tomography and control of electromagnetic hyperthermia equipments.

利用同轴探针、矢量网络分析仪和射频功率源，提出了一种测量小范围内组织介电常数温度依赖性的新方法。所研制的同轴探头不仅可用于介电常数测量，还可用于测量小范围内的温升。根据不同温度下测量的复介电常数计算了介电常数的温度系数。在整个研究过程中，我们取得了以下成果.明确了同轴探头的测量范围.研制了一种同轴探头，该探头配备了四个小型温度传感器，用于测量感兴趣的小区域内的介电常数和发热.提出了一种测量区域内平均温度变化的估计方法。5.估计的温度系数与用另一种方法得到的模拟组织体模复介电常数温度系数吻合较好。提出了一种在体测量组织介电常数温度系数的方法。该方法可用于测量各种组织的介电常数随温度的变化。温度依赖性的信息被用于微波计算机断层扫描和电磁热疗设备的控制的非侵入性温度映射。