Prescription for health promotion with combined use of health-, fitness-, and lifestyle markers

许多流行病学研究表明，运动可以预防心血管疾病和癌症。然而，运动处方尚未建立。以爱知县保健中心综合健康检查和体能检查（第一项研究）和体育锻炼计划（第二项研究）的参加者为研究对象，在不使用昂贵器械和不进行侵入性运动的情况下，尝试估算“无氧阈（AT）“作为最佳运动强度（第一项研究），并分析体育锻炼计划对冠心病危险因素的影响（第二项研究）。对健康与体质相关指标进行了单变量和多变量分析，第一项研究采用指标间相关分析确定最佳拟合模型，以最大摄氧量（VO_<2max>）和AT为因变量，其他生物指标为自变量，进行多元回归分析，建立男女回归方程。在第二项研究中，我们进行了为期6个月的AT水平运动计划，结果表明：（1）体脂、收缩压、舒张压、总胆固醇和甘油三酯显著降低，AT和VO<2max>显著升高;（2）轻度恶化组总胆固醇和空腹血糖的改善优于重度恶化组; 3）健康指标的改善与体质指标的改善相关。本研究开发了一种新的可行的运动处方，并显示了其实用性。

Many epidemiological studies showed that exercise was protective against cardiovascular diseases and cancers. Prescription of exercise, however, has not established yet. We tried to estimate "anaerobic threshold (AT) " as an optimal exercise strength without costly machines nor invasion (first study), and analyzed the effects of the programd physical exercise on coronary risk factors (second study).The subjects were participants of the comprehensive health check and fitness check (first study), and those of the physical exercise program (second study) at Aichi Prefectural Center of Health Care. We carried out single-and multi-variate analyzes for health-and fitness-related markers.In the first study, 1) we determined the best-fit model using an inter-marker correlation analysis, 2) performed a multiple regression procedure substituting maximum oxygen uptake (VO_<2max>) and AT for dependent variables and the other biological markers for independent variables, 3) made up a regression equation for each sex. The correlation coefficients between the predicted and the measured values were 0.53-0.78.In the second study, we carried out a 6-month AT-leveled exercise program, and elucidated that 1) body fat, systolic and diastolic blood pressure, total cholesterol, and triglycerides were significantly decreased, and AT and VO_<2max> were significantly increased ; 2) total cholesterol and fasting plasma glucose were improved among the mildly deteriorated subjects better than the severely deteriorated ones ; 3) improvement of health markers were associated with that of fitness markers.In this study, we developed a new feasible exercise prescription and showed its usefulness.