Anti-tumor effect of green tea and juice on.rat urinary bladder tumor inducd by BBN
Anti-tumor effect of green tea and juice on.rat urinary bladder tumor inducd by BBN
批准号:
06671619
负责人:
MATSUSHIMA Masahiro
金额:
$1.28万
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1994
资助国家:
日本
项目状态:
已结题
起止时间:
1994 至 1995
中文摘要
1)将Wistar大鼠分为6组,在饮水中加入0.05%的BBN,连续5周。对照组饮用自来水,第2组饮用绿茶,第3组饮用马卡,第4组饮用Hoji cho,第5组饮用乌龙茶,第6组饮用红茶。结果:40周后处死大鼠。在每只大鼠的肿瘤数量和大小方面,绿茶和Hoji Cha组与对照组之间存在显著差异。而马茶、乌龙茶、红茶组与对照组之间无显著差异。结论:绿茶对BBN所致大鼠膀胱肿瘤有抗肿瘤作用,半发酵茶(乌龙茶)和发酵茶(红茶)无…。更能发挥膀胱肿瘤的抗肿瘤作用。表没食子儿茶素没食子酸酯和表没食子儿茶素没食子酸酯:绿茶冲剂的主要多酚成分和抑瘤作用,在红茶和乌龙茶中明显低于绿茶。2)将Wistar大鼠分为4组,在饮水中加入0.05%的BBN,连续5周。对照组饮用自来水,第2组换蔬菜汁,第3组换胡萝卜汁,第4组换氟汁。结果:40周时处死大鼠。在每只大鼠的肿瘤数量和大小方面,组2与对照组之间有显著差异。结论:蔬菜汁对BBN诱导的大鼠膀胱癌有抗肿瘤作用,而胡萝卜汁和氟化汁对BBN诱导的大鼠膀胱肿瘤无抗肿瘤作用。较少
英文摘要
1) we divided Wistar rats into 6 groups and BBN was added to their drinking water in a concentration of 0.05% for 5 weeks. After that, the drinking water was replaced by tap water for the control group, green tea for group 2, macha for group 3, hoji cho for group 4, oolong tea for group 5 and black tea for group 6.Results : All rats were sacrificed at 40 weeks. Regarding the number and size of the tumors per rat, ther were significant differences between the groups such as green tea and hoji cha , and the control group. However, ther were no significant differences between the groups such as macha, oolong tea and black tea, and the control group. There were also significant differences regarding the tumor size per rat between the groups such as green tea and hoji cha, and the groups sush as oolong tea and black tea.Conclusions : The green tea had anti-tumor effect of urinary bladder in rat induced by BBN.The half-fermented tea (oolong tea) and the fermented tea (black tea) did not have … More anti-tumor effect of urinary bladder tumor. Epigallocathechin and epigallocathechin gallate : main polyphenolic constituent of green tea infusion and inhibit tumor promotion, is much lower in black tea and oolong tea than green tea.2) We devided Wistar rats into 4 groups and BBN was added to their drinking water in a concentration of 0.05% for 5 weeks. After that, the drinking water was replaced by tap water for the control group, vegetable juice for group 2, carrot juice for group 3 and fluit juice for group 4.Results : all rats were sacrificed at 40 weeks. Regarding the number and size of the tumor per rat, ther were significant differences between the group 2 and the control group. However, ther were no significant differences between the groups such as carrot and fulit juice, and the control group.Conclusions : The vegetable juice had anti-tumor effect of urinary bladder tumor induced in rat by BBN.However, the carrot juice and fluit juice had no anti-tumor effect of urinary bladder tumor induced in rat by BBN. Less
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Masayuki Harada, Naoko Tokuda and Masahiro Matsushima: "Anti-tumor effect of green tea on rat urinary bladder tumor induced by N-buthl-N- (4-hydroxybutyl) nitrosamine" J.Med.Soc.Toho. (in press).
Masayuki Harada、Naoko Tokuda 和 Masahiro Matsushima:“绿茶对 N-丁基-N-(4-羟丁基)亚硝胺诱导的大鼠膀胱肿瘤的抗肿瘤作用”J.Med.Soc.Toho。
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通讯作者:
Masahiro Matsushima: "The inhibitory effect of green tea on vesical oncogensis" Proceeding of Akutual Urologie. (in press). (1996)
Masahiro Matsushima:“绿茶对膀胱癌发生的抑制作用”Akutual Urologie 论文集。
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松島正浩,原田昌幸,徳田直子: "膀胱発癌に対する緑茶の抑制効果" Molecular Medicine. 31. 1274 (1994)
Masahiro Matsushima、Masayuki Harada、Naoko Tokuda:“绿茶对膀胱癌的抑制作用”《分子医学》31. 1274 (1994)。
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Masahiro Matsushima: "The inhibitory effect of green tea on vesical oncogenesis" Proceeding of Akutual Urologie. (in press).
Masahiro Matsushima:“绿茶对膀胱肿瘤发生的抑制作用”Akutual Urologie 论文集。
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松島正浩,原田昌幸,徳田直子: "膀胱発癌とお茶の効用" Molecular Medicine. 32. 987-988 (1995)
Masahiro Matsushima、Masayuki Harada、Naoko Tokuda:“膀胱癌发生和茶的影响”《分子医学》32. 987-988 (1995)。
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共 12 条
Anti - tumor Effect of Japanese favorite foods (buckwheat flour, soybean flour, unpolished rice tea and green tea) in BBN-induced rat bladder tumor
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批准号:12671562
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.02万
-
财政年份:2000
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负责人:MATSUSHIMA Masahiro
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依托单位:
Effects of Growth and thyroid hormones on the renal development in hormone-deficiency mice.
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批准号:04670983
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$0.45万
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财政年份:1992
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负责人:MATSUSHIMA Masahiro
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依托单位:
Study on Testicular in Animals with Congenital Hormone Deficiency
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批准号:02670724
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1990
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负责人:MATSUSHIMA Masahiro
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依托单位:
海外基金