Anti - tumor Effect of Japanese favorite foods (buckwheat flour, soybean flour, unpolished rice tea and green tea) in BBN-induced rat bladder tumor

绿茶在日本有着悠久的历史，其抗菌、抗炎、抗过敏和降压的疗效也经常被报道。本实验表明，绿茶可以抑制肿瘤生长，具有最强的抗癌作用。绿茶可改善肿瘤的组织学分级，并有降低肿瘤侵袭深度的趋势。绿茶可能会抑制肿瘤的发生。与致癌前喝绿茶的时间进行比较还没有调查，还需要进一步的调查。据报道，日本习惯食用的传统食物，如荞麦粉、Kinako和糙米茶对健康有好处。这些食物被含糊地说是有效的，几乎没有人研究过，尽管它们一直被融入我们的日常生活。此前，我们曾报道过绿茶的抗肿瘤作用。这一次，我们从抗肿瘤作用的角度研究了这些食物，并与绿茶进行了比较。荞麦粉和Kinako在肿瘤发生率和产生的肿瘤广告数上没有统计学差异，但总肿瘤体积减少了一半以上，被认为是有效的保健食品。4组(绿茶)和5组(绿茶和粗米茶)BBN诱发膀胱癌的异型性和侵袭深度明显降低。

Green tea has enjoyed a long history as a favorite drink in Japan and its therapeutic effects have frequently been reported with regard to its antibacterial, anti-inflammatory, anti-allergic and anti-hypertensive effect.This experiment suggested that green tea may inhibit tumor growth and have the strongest anticancer. Green tea improved the histologic grade of carcinomas and tends to decrease the depth of invasion. Green tea may inhibit tumor initiation. Comparison by the period giving green tea in advance of the carcinogen has not been investigated and it requires a further investigation.Traditional foods, such as buckwheat flour, Kinako and unpolished rice tea taken habitually in Japan have been reported to be good for health. These foods are vaguely said to be effective and have hardly been studied, despite their having always been integrated into our daily lives. Previously we reported on the anti-tumor effect of green tea. This time we study these foods from the aspect of their anti-tumor effect and also in comparison with green tea. With Buckwheat flour and Kinako, no statistically significant differences was found as to the tumor incidence and adverage number of tumors produced, but the total tumor volume decreased by more than half, so they are considered effective as health foods. In the group with unpolished rice tea added, statistically significant differences were comfirmed, so their anticancer effects can be expected.Atypia and the depth of invasion of BBN-induced bladder cancer was significantly decreased in group 4 (green tea) and group 5 (green tea and unpolished rice tea).