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Effects of Exercise on Blood Pressure, EEG and PWC.

运动对血压、脑电图和 PWC 的影响。

基本信息

批准号：
06680100
负责人：
MORITANI Toshio
金额：
$ 1.41万
依托单位：
KYOTO UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1994
资助国家：
日本
起止时间：
1994 至 1995
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-06680100/
关键词：
Exercise Blood Pressure EEG Autonomic nervous system 血圧大動脈脈波伝達速度

项目摘要

We examined the acute effects of aerobic exercise upon cardiac sympatho-vagal activities, beta-endorphin, atrial and brain natriuretic peptides (ANP and BNP), and EEG changes associated with postexercise hypotension. Eight adult male subjects volunteered for this study and visited laboratory on separate days for resting control (C,30-min quiet resting) and exercise (EX,30-min ride on a cycle ergometer, 50% of heart rate range) at random. Measurements were consisted of beat-by-beat systolic and diastolic blood pressures (SBP and DBP), cardiac sympatho-vagal activities (ECG R-R interval power spectral analysis : sympathetic activity index, SNS,and para-sympathetic activity index, PNS) and EEG frequency power spectral analyzes. In addition, plasma beta-endorphin, ANP,BNP,catecholamine, aldosterone and renin activity were measured immediately before, during and 30-min after the experimental treatments. Results indicated that none of these measurements showed any significant changes during C condition. There were however significant decreases in SBP and DBP after EX (p<0.05). These changes were accompanied by significant increases in ANP and BNP observed during EX and significant postexercise increases in para-sympathetic activity (*PNS index), EEG alpha wave component and beta-endorphin together with significant decreases in SNS index and delta wave component (p<0.05). Changes in alpha wave component were significantly correlated (r=0.56, p<0.05) with relative changes in beta-endorphin. These data suggest that a moderate exercise could bring about postexercise hypotension by modulating natriuretic peptides and beta-endorphin levels with subsequent changes in autonomic nervous system activities.

我们研究了有氧运动对心脏交感-迷走神经活动、β-内啡肽、心房和脑钠肽（ANP和BNP）以及运动后低血压相关EEG变化的急性影响。8名成年男性受试者自愿参加本研究，并在不同的日子随机访问实验室进行休息对照（C，30分钟安静休息）和运动（EX，骑自行车30分钟，心率范围的50%）。测量包括逐搏收缩压和舒张压（SBP和DBP）、心脏交感-迷走神经活动（ECG R-R间期功率谱分析：交感活动指数（SNS）和副交感活动指数（PNS））和EEG频率功率谱分析。此外，血浆β-内啡肽，心钠素，脑钠素，儿茶酚胺，醛固酮和肾素活性测定前，期间和30分钟后的实验治疗。结果表明，在C条件下，这些测量均未显示出任何显著变化。收缩压和舒张压在呼气后显著下降（p<0.05）。这些变化伴随着在EX期间观察到的ANP和BNP的显著增加以及运动后交感神经活动（*PNS指数）、EEG α波成分和β-内啡肽的显著增加，以及SNS指数和δ波成分的显著降低（p<0.05）。α波成分的变化与β-内啡肽的相对变化显著相关（r=0.56，p<0.05）。这些数据表明，适度运动可以通过调节利钠肽和β-内啡肽水平以及随后的自主神经系统活动变化来引起运动后低血压。