Establishment of Exercise Prescription Based On Cardiac Autonomic Activity

基于心脏自主活动的运动处方的制定

• 批准号: 11480011
• 负责人: MORITANI Toshio
• 金额: $ 5.06万
• 依托单位: KYOTO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 1999
• 资助国家: 日本
• 起止时间: 1999 至 2001
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-11480011/
• 关键词: Cardiac Autonomic Activity; Natriuretic Hormones; Heart Rate Variability Power; Obesity; 運動療法; 安全作業閾値; 運動処方; 心拍変動スペクトル

The purpose of this study was to establish exercise prescription based upon cardiac autonomic nervous system activity (Vagal Activity Threshold : VAT) and to evaluate the efficacy of this "Safety Exercise Threshold" determined by individual VAT. We first developed a new computer-aided analysis system for allowing a direct evaluation of cardiac autonomic activity particularly the parasympathetic (vagal) activity by means of ECG R-R interval power spectral and heart rate acceleration-deceleration power analyses, respectively. Fifty-one male college students and 13 patients with congestive heart failure were tested during incremental exercise stress test. Results indicated that our method of determining safety exercise threshold based on cardiac parasympathetic nervous activity was quite effective and could be used to even evaluate myocardial functions of the heart failure patients. In the subsequent studies, we actually used this safety exercise threshold for exercise prescription of obe … More se women who manifested high risk factors for life-style related diseases. Twelve weeks of exercise training results in significant improvements in lipid profile, blood pressure, percent body fat, and autonomic nervous system activity. Furthermore, exercise intervention experiment at VAT indicated that ET-1, catecholamine, and BNP levels were not significantly different before and after exercise! However, ANP levels increased,significantly after exercise (pre-exercise: 18.6±5.38 pg/ml vs post-exercise: 44.0±24.87, P < 0.001), which in turn brought about a significant post-exercise reduction in the blood pressure (SBP: 117.6±13.7 mmHg vs. 110.5±7.4, P <0.05, DBF: 78.6±6.7 vs. 73.5±6.6, P <0.01). Our data suggest that it is possible to determine the exercise intensity (VAT) on the basis of cardiac vagal response. These results also suggest that exercise at VAT level is safe exercise intensity in the light of cardiac stress, and that VAT may be recommended for individuals including obese people who might possess lower cardiac sympatho-vagal activity. Less

本研究的目的是建立基于心脏自主神经系统活动（迷走神经活动阈值：VAT）的运动处方，并评价由个体VAT确定的“安全运动阈值”的有效性。我们首先开发了一个新的计算机辅助分析系统，允许直接评估心脏自主活动，特别是副交感神经（迷走神经）活动的ECG R-R间期功率谱和心率加速-减速功率分析，分别。对51名男大学生和13名充血性心力衰竭患者进行递增负荷运动负荷试验。结果表明，根据心脏副交感神经活动确定安全运动阈值的方法是有效的，可用于心力衰竭患者心肌功能的评价。在随后的研究中，我们实际上使用了这个安全运动阈值来为obe制定运动处方 ...更多信息 这些妇女表现出生活方式相关疾病的高危因素。12周的运动训练可以显著改善血脂、血压、体脂百分比和自主神经系统活动。此外，在VAT的运动干预实验表明，ET-1，儿茶酚胺和BNP水平运动前后没有显着差异！然而，ANP水平在运动后显著升高，运动前18.6± 5.38pg/ml，运动后44.0± 24.87pg/ml，P < 0.001收缩压（SBP）：117.6±13.7 mmHg vs. 110.5±7.4，P <0.05;舒张压（DBF）：78.6±6.7 vs. 73.5±6.6，P <0.01。我们的数据表明，它是可能的，以确定运动强度（VAT）的基础上，心脏迷走神经反应。这些结果也表明，在VAT水平的运动是安全的运动强度，在心脏应激的光，增值税可能被推荐用于个人，包括肥胖的人谁可能拥有较低的心脏交感迷走神经活动。少

项目成果

Ue H,Masuda I,Yoshitake y Inazumi T,Moritani T.: "Assessment of cardiac autonomic nervous activities by means of ECG R-R interval power spectral analysis and cardiac depolarization-repolarization process"Annals of Noninvasive Electrocardiology. 5. 336-345

Ue H、Masuda I、Yoshitake y Inazumi T、Moritani T.：“通过心电图 R-R 间期功率谱分析和心脏除极-复极过程评估心脏自主神经活动”无创心电学年鉴。

Matsumoto, T., Miyawaki, C., Ue, H., Kanda, T., Yoshitake, Y., Moritani, T.: "Comparison of thermogenic sympathetic response to food intake between obese and non-obese young women"Obesity Research. 9(2). 78-85 (2001)

Matsumoto, T.、Miyawaki, C.、Ue, H.、Kanda, T.、Yoshitake, Y.、Moritani, T.：“肥胖和非肥胖年轻女性对食物摄入的产热交感神经反应的比较”肥胖研究

Matsumoto,T, Miyawaki, C., Ue, H, Kanda, T, Yoshitake, Y. Moritani, T: "Comparison of thermogenic sympathetic response to food intake between obese and non-obese young women"Obesity Research. 9(2). 78-85 (2001)

Matsumoto,T、Miyawaki, C.、Ue, H、Kanda, T、Yoshitake, Y. Moritani, T：“肥胖和非肥胖年轻女性对食物摄入的产热交感神经反应的比较”肥胖研究。

Amano, M., Kanda, T., Ue, H, Moritani T: "Exercise training and autonomic nervous system activity in obese individuals"Medicine and Science in Sports and Exercise. 33. 1287-1291 (2001)

Amano, M.、Kanda, T.、Ue, H、Moritani T：“肥胖个体的运动训练和自主神经系统活动”运动和运动中的医学和科学。

Kanda T, Nakamura E, Moritani T, Yamori Y.: "Arterial pulse wave velocity and risk factors for peripheral vascular disease"European Journal of Applied Physiology. 82. 1-7 (2000)

Kanda T、Nakamura E、Moritani T、Yamori Y.：“动脉脉搏波速度和周围血管疾病的危险因素”欧洲应用生理学杂志。