权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Control of Environmental Responses on the Surface of Multiphase Polymers for Molecular Design of Biomaterials

用于生物材料分子设计的多相聚合物表面环境响应控制

基本信息

批准号：
06680850
负责人：
SHIOMI Tomoo
金额：
$ 1.34万
依托单位：
Nagaoka University of Technology
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1994
资助国家：
日本
起止时间：
1994 至 1995
项目状态：
已结题

项目摘要

The surface study is very important for molecular design of polymeric biomaterials because the materials interact with organism on their surface but not in the bulk. In particular, the polymer surface may be changeable by responding to environment because of its low surface energy and flexible molecules. The purpose of this study is to clarify the mechanism of the formation and environmental responses of the surface for multiphase polymers and to establish synthesis methods of the functional polymers having environmental responsibility. The results obtained in this study are as follows :Various multiphase copolymers were synthesized in the techniques of telechelic polymers and macromonomers. In formation of the polymer surface in an air atmosphere the surface was covered by the low surface energy component, but in immersion in water the surface composition was rearranged rapidly to be covered almost completely by another component, and such compositional rearrangement was reversible. This ability was greater for graft copolymers than for block copolymers. For the three-component graft copolymers having a block copolymer as a graft three-layr structure was observed in the vicinity of the surface. This suggests that the graft component chains have a unique conformation near the surface owing to the surface energy difference between their components. Furthermore, environmental responses were studied for the copolymers having glassy and crystalline component chains. The glassy component showed environmental responsibility on the surface. This may mean that the glass transition temperature on the surface is lower than that in the bulk. On the other hand, the crystalline components were rigid for responsibility.

高分子生物材料与生物体的相互作用主要发生在材料的表面而非本体，因此材料的表面研究对于高分子生物材料的分子设计具有重要意义。特别地，聚合物表面由于其低表面能和柔性分子而可以通过响应环境而改变。本研究的目的是阐明多相聚合物表面的形成机理和环境响应机理，并建立具有环境响应性的功能聚合物的合成方法。主要研究结果如下：采用遥爪聚合物和大分子单体技术合成了多种多相共聚物。在空气气氛中形成聚合物表面时，表面被低表面能组分覆盖，但在水中浸渍时，表面组成迅速重排，几乎完全被另一组分覆盖，并且这种组成重排是可逆的。这种能力是更大的接枝共聚物比嵌段共聚物。对于具有嵌段共聚物作为接枝物的三组分接枝共聚物，在表面附近观察到三层结构。这表明接枝组分链由于其组分之间的表面能差异而在表面附近具有独特的构象。此外，环境响应进行了研究具有玻璃态和结晶组分链的共聚物。玻璃状组分在表面上表现出环境响应性。这可能意味着表面上的玻璃化转变温度低于本体中的玻璃化转变温度。另一方面，晶体组件是刚性的责任。