Automatic scanner for whole slide imaging

用于整个载玻片成像的自动扫描仪

• 批准号: 445121385
• 金额: --
• 依托单位: Technische Universität Dresden
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2020
• 资助国家: 德国
• 起止时间: 2019-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/445121385?language=en
• 关键词: Automatic; scanner; whole; slide; imaging

Many users of the Core Facility Cellular Imaging (CFCI) have to image whole series of slides. Using the currently available microscopes in our core facility, this is a very time consuming process. It would be much more time efficient to acquire the data by using an automated microscope with standardized procedures. This can be achieved with an automatic slide scanner that can be loaded with up to 100 slides per single run. Data can be collected in a fully automated way by applying individual user settings, enabling standardized image acquisition with high reproducibility. Series of samples can be recorded over night to increase the efficiency of data collection. This leads to an enormous reduction in time necessary for the users to operate the microscope during imaging. The microscope of choice should be used to analyze both brightfield as well as fluorescent samples. It offers a broad spectrum of analysis to the users of our core facilty. Due to this automatic calibration, reproducible and consistent data can be acquired for further quantifications and analyses.

许多核心设备细胞成像(CFCI)的用户必须对整个系列的幻灯片进行成像。使用我们核心设施中目前可用的显微镜，这是一个非常耗时的过程。通过使用具有标准化程序的自动显微镜来获取数据将会更省时。这可以通过一台自动幻灯片扫描仪实现，该扫描仪每次运行最多可以加载100张幻灯片。通过应用个人用户设置，可以以完全自动化的方式收集数据，从而实现标准化的图像采集，并具有高度的重复性。可以在夜间记录一系列样本，以提高数据收集的效率。这大大减少了使用者在成像过程中操作显微镜所需的时间。所选的显微镜既可用于分析亮场样品，也可用于分析荧光样品。它为我们核心设施的用户提供了广泛的分析。由于这种自动校准，可以获得可重复和一致的数据，以供进一步量化和分析。