University of Iowam - Whole Body 7T MRI Scanner

爱荷华大学 - 全身 7T MRI 扫描仪

• 批准号: 7834427
• 负责人: VINCENT A MAGNOTTA
• 金额: $ 796.93万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7834427
• 关键词: Agreement; Animals; Arts; Award; Brain; Brain Mapping; Brain imaging; Businesses; Cancer Center; Clinical; Commit; Development; Electronics; Engineering; Faculty; Fees; Funding; Grant; Housing; Human; Image; Image Analysis; Imagery; Institutes; Iowa; Laboratories; Magnetic Resonance Imaging; Medical; Medicine; Nuclear; Orthopedics; Performance; Public Health; Research; Research Personnel; Research Support; Resolution; Running; Scanning; Science; Spectrum Analysis; System; Technical Expertise; Time; Translations; United States National Institutes of Health; Universities; Work; bioimaging; cardiovascular imaging; college; design; image processing; imaging modality; instrument; interest; member; novel; public health relevance; research facility; response; square foot; systems research; tumor

DESCRIPTION (provided by applicant): The University of Iowa is requesting funds to support the purchase of a state-of-the-art Siemens seven Tesla whole body MRI system to support the research efforts of 33 funded NIH investigators from five colleges (Medicine, Engineering, Public Health, Liberal Arts and Sciences, and Business) with 40 NIH grants. This group of researchers has a wide range of interests including: functional brain mapping, high-resolution anatomical imaging of the brain, spectroscopy of the brain, pH dynamics, orthopedic imaging, evaluation of tumor response to treatment, and cardiovascular imaging. This system would be the only whole body ultra-high field (>3T) MRI scanner on campus or within 200 miles. The scanner will be located within a new 200,000 square foot, $130 million, research building located on the medical campus. This facility will house four new human scanner bays and nine animal imaging bays. The human imaging facilities will include three exam/changing rooms, an electronics shop, image processing and visualization laboratories. The proposed 7T scanner will significantly advance the research efforts at the University of Iowa by allowing higher spatial resolution images to be acquired, increased SNR, faster scan times, increased spectral resolution for spectroscopic studies, and 23Na images to be acquired. The proposed scanner is state of the art and includes 1) 128 receive and 8 transmit channels; 2) broad band receiver; 3) high performance gradients; 4) active shielding; and 5) multi-nuclear coils. The MR Research Facility that currently administers existing 1.5T and 3T whole body research systems will manage the proposed 7T scanner. Significant technical expertise exists at the University of Iowa to take full advantage of this scanner and to develop new novel imaging sequences. In addition, the University of Iowa has committed to hiring a new faculty member with expertise in coil design and development. A board-certified MR technologist will also be hired to run this system. Revenues to support other facility expenses will come from user fees. The MR Research Facility already has an internal and external advisory board that will continue in this capacity and will integrate the proposed 7T scanner. The MR research facility is under the Iowa Institute of Biomedical Imaging (IIBI) and is integrated into the University of Iowa's Clinical and Translation Science Award (CTSA) and the NCI funded cancer center. The University of Iowa already has established a Master Research Agreement with Siemens and has developed collaborative efforts for many of the proposed projects included in this application. PUBLIC HEALTH RELEVANCE: A 7T whole body MRI scanner will facilitate the research of 33 NIH funded investigators at the University of Iowa. Their work will be enhanced by the finer detail available from the images. This instrument will also allow new imaging methods to be used that currently are not available at lower field strengths.

描述（由申请人提供）：爱荷华大学正在申请资金，以支持购买最先进的西门子7特斯拉全身MRI系统，以支持来自五个学院（医学，工程，公共卫生，文科和理科以及商业）的33名NIH资助的研究人员的研究工作。这组研究人员兴趣广泛，包括：脑功能测绘、脑高分辨率解剖成像、脑光谱、pH动力学、骨科成像、肿瘤治疗反应评估和心血管成像。该系统将是校园内或200英里内唯一的全身超高场（bbb3t）核磁共振扫描仪。该扫描仪将被安置在一个新的20万平方英尺，耗资1.3亿美元的研究大楼内，该大楼位于医学院。该设施将容纳4个新的人体扫描仪舱和9个动物成像舱。人体成像设施将包括三个考试/更衣室、一个电子商店、图像处理和可视化实验室。提出的7T扫描仪将大大推进爱荷华大学的研究工作，允许获得更高的空间分辨率图像，提高信噪比，更快的扫描时间，提高光谱研究的光谱分辨率，并获得23Na图像。所提议的扫描器是最先进的，包括1)128个接收通道和8个发送通道；2)宽带接收机；3)高性能梯度；4)主动屏蔽；5)多核线圈。目前管理现有1.5T和3T全身研究系统的MR研究机构将管理拟议的7T扫描仪。在爱荷华大学存在着重要的技术专长，可以充分利用这种扫描仪并开发新的成像序列。此外，爱荷华大学已承诺聘请一位具有线圈设计和开发专业知识的新教员。还将聘请一名经认证的磁共振技术专家来运行该系统。用于支持其他设施费用的收入将来自用户费用。核磁共振研究机构已经有了一个内部和外部的咨询委员会，将继续发挥这一作用，并将整合拟议的7T扫描仪。MR研究设施隶属于爱荷华生物医学成像研究所（IIBI），并被整合到爱荷华大学的临床和翻译科学奖（CTSA）和NCI资助的癌症中心。爱荷华大学已经与西门子建立了一个硕士研究协议，并为本申请中包含的许多拟议项目开展了合作。