Molecular mechanism of transcription factor controlling plant immunity and its application in the production of pathogen-resistant plants.

转录因子控制植物免疫的分子机制及其在抗病植物生产中的应用

• 批准号: 19208004
• 负责人: YOSHIOKA Hirofumi
• 金额: $ 28.7万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (A)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-19208004/
• 关键词: シグナル伝達; 植物免疫; WRKY型転写因子; 耐病性植物; MAPキナーゼ; 植物病理学; 植物; 病理学; 転写因子

Mitogen-activated protein kinase (MAPK) cascades have pivotal roles in plant innate immunity. However, downstream signaling of plant defense-related MAPKs is not well understood. Here we provide evidence that Nicotiana benthamiana WRKY8 is a physiological substrate of SIPK, NTF4, and WIPK. Phosphorylation of WRKY8 increased its DNA-binding activity. MAPK-mediated phosphorylation of WRKY8 has an important role in the defense response through activation of downstream genes.

丝裂原活化蛋白激酶（MAPK）级联在植物先天免疫中起关键作用。然而，植物防御相关MAPKs的下游信号传导尚不清楚。本研究证明，本烟WRKY8是SIPK、NTF4和WIPK的生理底物。WRKY8的磷酸化增加了其dna结合活性。mapk介导的WRKY8磷酸化通过激活下游基因在防御反应中发挥重要作用。

项目成果

The role of radical burst via MAPK signaling in plant immunity

• DOI: 10.4161/psb.6601
• 发表时间: 2008-07
• 期刊: Plant Signaling & Behavior
• 影响因子: 2.9
• 作者: S. Asai;H. Yoshioka

Riboflavin synthesis participates in plant immune responses in Nicotiana benthamiana

核黄素合成参与本塞姆氏烟草的植物免疫反应

• 发表时间: 2009
• 作者: 伊藤智和;邊児久;吉村徹;他;浅井秀太
• 通讯作者: 浅井秀太

StCDPK5のvaluabieドメインおよびkinaseドメインがStRBOHBの活性化に重要である

StCDPK5 的有价值结构域和激酶结构域对于 StRBOHB 激活很重要

• 发表时间: 2009
• 作者: Ishiwata;Shin'ichi;山田早人・池田素子・小林迪弘;西田睦;渡邉一哉;吉原 弘貴・内海 好規・藤田 直子・佐藤 光・中村 保典;浅井秀太・市川達士・小林光智衣・上吉原裕介・森仁志・吉岡博文
• 通讯作者: 浅井秀太・市川達士・小林光智衣・上吉原裕介・森仁志・吉岡博文

MAPK signaling regulates nitric oxide and NADPH oxidase-dependent oxidative bursts in Nicotiana benthamiana

• DOI: 10.1105/tpc.107.055855
• 发表时间: 2008-05-01
• 期刊: PLANT CELL
• 影响因子: 11.6
• 作者: Asai, Shuta;Ohta, Kohji;Yoshioka, Hirofumi
• 通讯作者: Yoshioka, Hirofumi

A key enzyme for flavin synthesis is required for nitric oxide and reactive oxygen species production in disease resistance

• DOI: 10.1111/j.0960-7412.2010.04206.x
• 发表时间: 2010-06-01
• 期刊: PLANT JOURNAL
• 影响因子: 7.2
• 作者: Asai, Shuta;Mase, Keisuke;Yoshioka, Hirofumi
• 通讯作者: Yoshioka, Hirofumi