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Whole genome association study of functional psychoses

Whole genome association study of functional psychoses
功能性精神病的全基因组关联研究
批准号:
19209040
负责人:
YOSHIKAWA Takeo
金额:
$28.79万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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中文摘要
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英文摘要
We performed whole genome association study of schizophrenia and bipolar disorder. For schizophrenia, we examined 100K SNPs (single nucleotide polymorphisms) using trio samples in the first stage, and in the second stage we used case-control samples. In the final stage, we examined Chinese quad samples. It is of note that in Japanese population, multiple GABAergic genes showed association with schizophrenia. For bipolar disorder, we examined 100K SNPs using case-control samples. We have published the data and made it open to public via an in house server.
期刊论文(13)
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会议论文
DOI: 10.1093/med/9780198713005.003.0070
发表时间: 2020-03
期刊: New Oxford Textbook of Psychiatry
影响因子: --
作者: [F. McMahon;S. Detera-Wadleigh]
通讯作者: F. McMahon;S. Detera-Wadleigh
DOI: --
发表时间: 2010
期刊: 神経化学 Vol.49(No.1)
影响因子: --
作者: [Nagafuchi S, Umene K, Yamanaka F, Oohashi S, Sinndo M, Kurisaki H, Kudoh J, Shimizu N, Hara T, Harada M., 森本幸裕・小林達明 編著, 山田和男]
通讯作者: 山田和男
DOI: 10.1002/ajmg.b.30941
发表时间: 2009-12-05
期刊: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS
影响因子: 2.8
作者: [Hattori, Eiji, Toyota, Tomoko, Yoshikawa, Takeo]
通讯作者: Yoshikawa, Takeo
統合失調症グルタミン酸系の遺伝基盤と治療への応用
谷氨酸系统在精神分裂症中的遗传基础及其治疗应用
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Yamazaki S, Iwama A, Morita Y, Eto K,Ema H, Nakauchi H, 吉川武男]
通讯作者: 吉川武男
7
    Identification of biomarkers for schizophrenia using scalp hairs
    Analysis of iPS cells from patients with 22q11.2 deletion and schizophrenia
    Inositol-metabolizing enzyme gene-manipulated mice towards molecular dissection of pathophysiology of mental disorders.
    • 批准号:
      17390323
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $9.98万
    • 财政年份:
      2005
    • 负责人:
      YOSHIKAWA Takeo
    • 依托单位:
    Identification of susceptibility genes for functional psychoses by whole genome scan
    • 批准号:
      12307020
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $22.84万
    • 财政年份:
      2000
    • 负责人:
      YOSHIKAWA Takeo
    • 依托单位:
    海外基金