Gene and protein location of Tumour Necrosis Factor(TNF)- αconvertingenzyme in gingival tissues from periodontitis with drug-induced gingival overgrowth.

药物性牙龈过度生长引起的牙周炎牙龈组织中肿瘤坏死因子（TNF）-α转换酶的基因和蛋白定位。

• 批准号: 23890062
• 负责人: ABE Daisuke
• 金额: $ 1.91万
• 依托单位: Niigata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Research Activity Start-up
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-23890062/
• 关键词: カルシウム拮抗薬剤性歯肉増殖症; TACE; TIMP-3; タンパク質発現解析; 遺伝子発現解析; 免疫組織化学; ｑRTーPCR解析; 免疫組織学的解析; 医療・福祉; 歯学; 歯周病学; 分子生物学; 酵素

The aim of the present study was to analyse mRNA expression of TACE and TIMP-3, and protein location of TACE in gingival tissue removed from drug-(calcium-channel blocker) induced GO and periodontitis.

本研究的目的是分析TACE和TIMP-3的mRNA表达，以及TACE在药物（钙通道阻滞剂）诱导的GO和牙周炎的牙龈组织中的蛋白定位。

项目成果

Gene and protein location of Tumour Necrosis Factor(TNF)- αconverting enzyme in gingival tissues from periodontitis with drug-induced gingival overgrowth

牙周炎合并药物性牙龈增生牙龈组织中肿瘤坏死因子(TNF)-α转换酶的基因和蛋白定位

• 期刊: Archives of Oral Biology
• 影响因子: 3
• 作者: Takayuki Tomita;Takehiko Kubota;Naohiro Nakasone;Toshiya Morozumi;Daisuke Abe;Satoshi Maruyama;Taro Shimizu;Makoto Horimizu;Takashi Saku and Hiromasa Yoshie
• 通讯作者: Takashi Saku and Hiromasa Yoshie

Gene and protein location of Tumour Necrosis Factor(TNF)- α converting enzyme in gingival tissues from periodontitis with drug-induced gingival overgrowth

牙周炎合并药物性牙龈过度生长牙龈组织中肿瘤坏死因子(TNF)-α转换酶的基因和蛋白定位

• 发表时间: 2012
• 作者: Takayuki Tomita;Takehiko Kubota;Naohiro Nakasone;Toshiya Morozumi;Daisuke Abe;Satoshi Maruyama;Taro Shimizu;Makoto Horimizu;Takashi Saku and Hiromasa Yoshie
• 通讯作者: Takashi Saku and Hiromasa Yoshie

Gene and protein localisation of tumour necrosis factor (TNF)-α converting enzyme in gingival tissues from periodontitis patients with drug-induced gingival overgrowth.

药物性牙龈过度生长的牙周炎患者牙龈组织中肿瘤坏死因子（TNF）-α转换酶的基因和蛋白定位。

• 发表时间: 2012
• 作者: 荒木保弘;Wei-chi Ku;石濱泰;大隅良典;Norio Aoyama;Takayuki Tomita
• 通讯作者: Takayuki Tomita