Construction of Epidemiological Model for Periodontal Disease

牙周病流行病学模型的构建

• 批准号: 09470469
• 负责人: MIYAZAKI Hideo
• 金额: $ 4.67万
• 依托单位: NIIGATA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B).
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 2000
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-09470469/
• 关键词: Periodontal disease; Epidemiology; Risk factor; 血糖値; 肝機能; 腎機能; 心臓所見

The Purpose of this research was to identify the risk factors for periodontal disease with odds ratio. Baseline survey was carried out on 599 persons aged 70-year-old and 162 persons aged 80-year-old in Niigata City in 1997. In cross sectional study, multiple logistic regression analysis showed variables that significant correlated to sever periodontal status were age, gender, number of teeth present, filled teeth, bridge abutment teeth. In longitudinal study, variables that significant correlated to periodontal disease progression were both maximum periodontal pocket depth and attachment loss at baseline, upper and lower molars, filled teeth and abutment teeth for removable partial denture.Gender, smoking and alcohol drinking habits were obtained using a questionnaire, while serum levels of disease markers were investigated and attachment levels were clinically recorded. For the assessment of periodontal disease progression, additional attachment loss was used if one or more sites had a 3mm or more increase in probing attachment level. Three hundred ninety four subjects(208 males and 186 females)were surveyed. Approximately 75 per cent of subjects exhibited additional attachment loss over a two-year period. Significant associations were found between additional attachment loss and smoking, and attachment level of 6mm or more at the baseline, with odds ratios of 3.75 and 2.29, respectively. Smoking habit and baseline attachment level of 6mm or more may be considered as risk factors for further attachment loss among healthy elderly people.

本研究的目的是用优势比确定牙周病的危险因素。1997年对新泻市599名70岁老人和162名80岁老人进行了基线调查。在横断面研究中，多元logistic回归分析显示，与牙周状况显著相关的变量为年龄、性别、牙数、补牙、基牙。在纵向研究中，与牙周疾病进展显著相关的变量是最大牙周袋深度和基线附着缺失、上臼齿和下臼齿、可摘局部义齿补牙和基牙。通过问卷调查获得性别、吸烟和饮酒习惯，同时调查血清疾病标志物水平，并记录临床依恋水平。对于牙周病进展的评估，如果一个或多个部位有3mm或更多的探探附着水平增加，则使用额外的附着损失。共调查了384名受试者（208名男性，186名女性）。在两年的时间里，大约75%的受试者表现出额外的依恋丧失。额外的依恋损失与吸烟和基线时的依恋水平大于或等于6毫米之间存在显著关联，比值比分别为3.75和2.29。吸烟习惯和基线依恋水平6mm及以上可能被认为是健康老年人进一步依恋丧失的危险因素。