Follow-up Study on Oral and Systemic Health in Elderly

老年人口腔及全身健康追踪研究

• 批准号: 21592644
• 负责人: MIYAZAKI Hideo
• 金额: $ 2.91万
• 依托单位: Niigata University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21592644/
• 关键词: コホート研究; 高齢者; 口腔と全身; 栄養; 死亡リスク

Elderly subjects surveyed between 1998 and 2008 were followed-up for 3 years from 2009 to 2011. Each subject or his/her family, if necessary, was interviewed about a medical history including cause of death, and received oral health and physical fitness examinations once a year. The results suggested that 1) bone metabolic markers influenced periodontal disease progression and decrease of bone mineral density, and also influenced mandibular inferior cortex related to bone stiffness and tooth loss, 2) a low total cholesterol serum level, low docosahexaenoic acid intake and dietary saturated fatty acids, respectively, influenced to periodontal disease progression, 3) non-smoking elderlies with root caries were at an elevated risk for dysrhythmias, and 4) low estimated glomerular filtration rate was a risk for cardiovascular disease occurrence and also for mortality.

1998年至2008年期间调查的老年受试者从2009年至2011年随访3年。如有必要，对每名受试者或其家人进行病史（包括死亡原因）访谈，并每年接受一次口腔健康和体能检查。结果提示：1）骨代谢指标影响牙周病的进展和骨密度的降低，也影响下颌骨下皮质与骨硬度和牙齿脱落有关; 2）低血清总胆固醇水平、低二十二碳六烯酸摄入量和低膳食饱和脂肪酸分别影响牙周病的进展，3）不吸烟的根面龋老年人患心律失常的风险增加; 4）肾小球滤过率估计值低是心血管疾病发生的风险，也是死亡的风险。

项目成果

Tooth-related risk factors for periodontal disease in community-dwelling elderly people

• DOI: 10.1111/j.1600-051x.2010.01565.x
• 发表时间: 2010-06-01
• 期刊: JOURNAL OF CLINICAL PERIODONTOLOGY
• 影响因子: 6.7
• 作者: Hirotomi, Toshinobu;Yoshihara, Akihiro;Miyazaki, Hideo
• 通讯作者: Miyazaki, Hideo

Dental Occlusal Destruction Affects Deterioration of Physical Fitness in Elderly

牙齿咬合破坏影响老年人体质恶化

• 发表时间: 2009
• 作者: Okuyama N;(代表)
• 通讯作者: (代表)

歯の数・口腔機能と健康,健康寿命を延ばす歯科保健医療,歯科医学的根拠とかかりつけ歯科医

牙齿数量、口腔功能与健康、延长健康寿命的牙科保健、牙科基础和家庭牙医

• 发表时间: 2009
• 作者: Sugihara;N.;Maki;Y.;Kurokawa;A.;and Matsukubo;T.;葭原明弘,宮崎秀夫,日本歯科総合研究機構
• 通讯作者: 葭原明弘,宮崎秀夫,日本歯科総合研究機構

Dietary ratio ofω-6 toω-3 polyunsaturated fatty acids and periodontal disease in a community-based older Japanese : a 3-year follow-up study

日本社区老年人中 ω-6 与 ω-3 多不饱和脂肪酸的膳食比例与牙周病：一项为期 3 年的跟踪研究

• 发表时间: 2010
• 作者: Iwasaki M;Taylor GW;Yoshihara A;Muramatsu K;Watanabe R;Miyazaki H
• 通讯作者: Miyazaki H

Relation of bone turnover markers to periodontal disease in elderly

骨转换标志物与老年人牙周病的关系

• 发表时间: 2010
• 作者: A. Yoshihara;Y. Hayashi;H. Miyazaki
• 通讯作者: H. Miyazaki