Development of advanced CAD system for mammography and its practical application

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The purpose of this research project is to develop an improved CAD system for mammography and to heighten the system performance. The main results are as follows.[1]System robust to variations of imaging conditionThe conventional CAD system has been installed is five medical institutions in Japan and its performance had been tested . Each medical institution has its own imaging conditions and the performance of the conventional system depends on them. We have developed new processing algorithm, which makes the CAD system insensitive to the variation of imaging conditions.[2]Revised tumor detection methodAdaptive ring filter has been developed, which makes it possible to detect tumors with rough and irregular density distributions. The performance of the adaptive ring filter has been shown to be superior to that of the iris filter.[3]Detection of tumors close to or attached to thoracic wallTumors close to or attached to thoracic wall tend to be missed by the conventional CAD system. The detection algorithm for them has been revised. That is, the candidates in the area near thoracic wall are recognized by the different algorithm developed by this project. The performance of the new system has become higher than that of the conventional system.[4]Advanced microcalcification detection methodCoarse-calcification causes false microcalcifications. We have developed a new method for coarse-calcification detection, which can help decreasing false microcalcification clusters. Complicated background can cause false microcalcifications. We have also developed an algorithm to exclude them.These methods described above have been installed in the new CAD system.