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Physical Responses in Chronic Pain Patients and Modifying Factors of Pain

慢性疼痛患者的身体反应和疼痛改变因素

基本信息

批准号：
11470525
负责人：
FUKAI Kiyoko
金额：
$ 8万
依托单位：
KAWASAKI UNIVERSITY OF MEDICAL WELFARE
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B).
财政年份：
1999
资助国家：
日本
起止时间：
1999 至 2000
项目状态：
已结题

项目摘要

1. This study confirmed that seventy-eight items in the McGill Pain Questionnaire (MPQ) (Melzack, 1975) are valid as pain terms by suitable Japanese translation. The other items that do not appear in MPQ were found. Understanding pain, it is important to consider time series pattern of pain intensity, physical environments, such as weather, social background of the patients and their psychological status.2. The pain thresholds of the chronic pain patients were higher than those of the healthy subjects. In some chronic pain patients, ACTH, β-endorphin can be observed in blood serum more than before they had had no pain. This indicates that chronic pain patients are in the stressful conditions.3. It is suggested that cutaneous blood flow volume at the inflammation area can be a pain indicator in chronic rheumatic arthritis patients4. It is found that patients sometimes experienced over-tolerate pain during the operations under local anesthesia.5. It is clarified that nursing analgesic cares, such as comfortable perfume and cold compress, are as effective as drugs in pain management. Moreover, combined analgesic cares are much more effective than a single care implementation.The ultimate aim of this research is "understanding pain more correctly" , and "developing comprehensive pain assessment tool that surpasses MPQ" . Therefore, the authors are continuing to study in various chronic pain patients. Then we plan to investigate interrelationship between the chronic pain and the behavior or the mental status of the subjects, and also between the pain and the physiological change in human body.

1. 本研究证实，麦吉尔疼痛问卷 (MPQ)（Melzack，1975）中的 78 个项目通过适当的日语翻译可作为疼痛术语。找到了 MPQ 中未出现的其他项目。了解疼痛，重要的是要考虑疼痛强度的时间序列模式、物理环境（例如天气）、患者的社会背景及其心理状态。2．慢性疼痛患者的疼痛阈值高于健康受试者。在一些慢性疼痛患者中，血清中可观察到ACTH、β-内啡肽比无疼痛前增多。这表明慢性疼痛患者处于紧张状态。3．提示炎症区域的皮肤血流量可以作为慢性风湿性关节炎患者的疼痛指标4。研究发现，局麻手术中患者有时会出现过度忍受疼痛的情况。5．研究表明，舒适的香水和冷敷等护理镇痛护理在控制疼痛方面与药物一样有效。而且，联合镇痛护理比单一护理实施效果要好得多。本研究的最终目的是“更正确地理解疼痛”，“开发超越MPQ的综合疼痛评估工具”。因此，作者正在继续对各种慢性疼痛患者进行研究。然后我们计划调查慢性疼痛与受试者的行为或精神状态之间的相互关系，以及疼痛与人体生理变化之间的相互关系。