Study of qualitative diagnostic ability using dynamic contrast-enhanced MRI in oral and maxillofacial region

口腔颌面部动态增强MRI定性诊断能力研究

• 批准号: 14370603
• 负责人: KISHI Kanji
• 金额: $ 8万
• 依托单位: OKAYAMA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14370603/
• 关键词: dynamic contrast-enhanced MRI; contrast index; CI curve; SCC; benign tumor; lymphoma; Salivary gland tumor; dynamic contrast enhanced MRI; 口腔腫瘍; dynamic MRI; CI-Curve

Dynamic contrast-enhanced MRI (DCE-MRI) is useful for differential diagnosis of some tumors and it has been used to identify the differences between benign and malignant tumors. We have also shown characteristic features of several lesions using DCE-MRI in head and neck regions as follows,1) In the sublingual tumors, the DCE-MRI may be useful in differentiating malignant from benign tumors, and in detecting the extent of the tumors in the sublingual carcinomas.2) In the solitary bone cyst, DCE-MRI can provide useful information for distinguishing solitary bone cysts from other cysts or tumors.3) In the squamous cell carcinomas, proliferating cell nuclear antigen labeling index shows a significant correlation with DCE-MRI parameters (maximum CI and maximum CI gain). The assessment of DCE-MRI parameters may provide valuable information for tumor cell proliferation of patients with oral cancer.4) After considering the various images of pleomorphic adenoma along with the possible types of lesions, pleomorphic adenoma might be diagnosed using the features visible with MRI and DCE-MRI.5) ICE-MRI might be useful for distinguishing malignant lymphoma from squamous cell carcinomas.6) The MRI and DCE-MRI features are characteristic features of adenomatoid odontogenic tumor and may be a basis for differentiating adenomatoid odontogenic tumor from the possible lesions in radiographic examinations.

动态对比增强磁共振成像（DCE-MRI）可用于某些肿瘤的鉴别诊断，并已用于识别良性肿瘤和恶性肿瘤之间的差异。我们还使用 DCE-MRI 显示了头颈部区域的几种病变的特征，如下所示：1）在舌下肿瘤中，DCE-MRI 可能有助于区分良恶性肿瘤，以及检测舌下癌中肿瘤的范围。2）在孤立性骨囊肿中，DCE-MRI 可以提供区分孤立性骨囊肿和其他囊肿的有用信息。 3）鳞状细胞癌中，增殖细胞核抗原标记指数与DCE-MRI参数（最大CI和最大CI增益）呈显着相关。 DCE-MRI参数的评估可以为口腔癌患者的肿瘤细胞增殖提供有价值的信息。4）在考虑多形性腺瘤的各种图像以及可能的病变类型后，可以利用MRI和DCE-MRI可见的特征来诊断多形性腺瘤。5）ICE-MRI可能有助于区分恶性淋巴瘤和鳞状细胞 6) MRI和DCE-MRI特征是牙源性腺瘤样肿瘤的特征性表现，可作为放射学检查中区分腺瘤样牙源性肿瘤与可能病变的依据。

项目成果

Yanagi Y, Asaumi J et al.: "Incidentally found and unexpected tumors discovered by MRI Examination for tenporomandibular joint arthrosis"Eur J Radiol. 47(1). 6-9 (2003)

Yanagi Y、Asaumi J 等人：“通过 MRI 检查对颞下颌关节关节病偶然发现和意外发现的肿瘤”Eur J Radiol。

Asaumi J, Yanagi Y et al.: "The value of dynamic contrast-enhanced MRI in diagnosis of malignant lymphoma of head and neck"Eur J Radiol. 48(2). 178-182 (2003)

Asaumi J、Yanagi Y 等：“动态对比增强 MRI 在头颈部恶性淋巴瘤诊断中的价值”Eur J Radiol。

Hisatomi M, Asaumi J, Konouchi H, Yanagi Y, et al.: "Assessment of dynamic MRI of Warthin's tumors arising as multiple lesions in the parotid glands"Oral Oncol. 38(4). 369-372 (2002)

Hisatomi M、Asaumi J、Konouchi H、Yanagi Y 等人：“腮腺多发性病变引起的沃辛肿瘤的动态 MRI 评估”Oral Oncol。

Hisatomi M, Asaumi J, Kishi K et al.: "Assessment of pleomorphic adenomas using MRI and dynamic contrast enhanced MRI"Oral Oncology. 39(6). 574-579 (2003)

Hisatomi M、Asaumi J、Kishi K 等人：“使用 MRI 和动态对比增强 MRI 评估多形性腺瘤”口腔肿瘤学。

Konouchi H, Asaumi J et al. c: "Evluation of tumor proliferation using dynamic contrast enhanced-MRI of oral cavity and oropharyngeal squamous cell carcinoma"Oral Oncol. 39(3). 290-295 (2003)

河内 H、浅海 J 等人。