Study of qualitative diagnostic ability using dynamic contrast-enhanced MRI in oral and maxillofacial region

动态增强磁共振成像(DCE-MRI)有助于某些肿瘤的鉴别诊断，已被用于鉴别良、恶性肿瘤。DCE-MRI还显示了几种头颈部病变的特征性特征：1)在舌下肿瘤中，DCE-MRI可用于鉴别良、恶性肿瘤，并有助于判断舌下癌的肿瘤范围。2)在孤立性骨囊肿中，DCE-MRI可为孤立性骨囊肿与其他囊肿或肿瘤的鉴别提供有用的信息。3)在鳞状细胞癌中，增殖细胞核抗原标记指数与DCE-MRI参数(最大CI和最大CI增益)显著相关。DCE-MRI参数的评估可能为口腔癌患者的肿瘤细胞增殖提供有价值的信息。4)在考虑到多形性腺瘤的各种图像以及可能的病变类型后，可以利用MRI和DCE-MRI所见的特征来诊断多形性腺瘤。5)ICE-MRI可能有助于鉴别恶性淋巴瘤和鳞状细胞癌。6)MRI和DCE-MRI征象是腺瘤样牙源性肿瘤的特征性征象，可能是鉴别腺瘤样牙本质瘤和X线检查中可能的病变的基础。

Dynamic contrast-enhanced MRI (DCE-MRI) is useful for differential diagnosis of some tumors and it has been used to identify the differences between benign and malignant tumors. We have also shown characteristic features of several lesions using DCE-MRI in head and neck regions as follows,1) In the sublingual tumors, the DCE-MRI may be useful in differentiating malignant from benign tumors, and in detecting the extent of the tumors in the sublingual carcinomas.2) In the solitary bone cyst, DCE-MRI can provide useful information for distinguishing solitary bone cysts from other cysts or tumors.3) In the squamous cell carcinomas, proliferating cell nuclear antigen labeling index shows a significant correlation with DCE-MRI parameters (maximum CI and maximum CI gain). The assessment of DCE-MRI parameters may provide valuable information for tumor cell proliferation of patients with oral cancer.4) After considering the various images of pleomorphic adenoma along with the possible types of lesions, pleomorphic adenoma might be diagnosed using the features visible with MRI and DCE-MRI.5) ICE-MRI might be useful for distinguishing malignant lymphoma from squamous cell carcinomas.6) The MRI and DCE-MRI features are characteristic features of adenomatoid odontogenic tumor and may be a basis for differentiating adenomatoid odontogenic tumor from the possible lesions in radiographic examinations.