Investigation between intestinal flora and general health status

肠道菌群与一般健康状况的调查

• 批准号: 22249019
• 负责人: NAKAJI Shigeyuki
• 金额: $ 19.88万
• 依托单位: Hirosaki University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (A)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-22249019/
• 关键词: 腸内細菌; 全体的健康度; T-RELP 法; OUT; 肥満; 加齢; 食事; 一般住民; T-RELP法; 健康度; 体力; 健康増進; 疫学; 疫学研究; T-RFLP法; ライフスタイル; Nagashima法; OTU

The association between intestinal flora and general health status were investigated among general populations. Following results were obtained; 1. Proportion of OTU657 and 990 increased with age, 2. Proportion of OTU940 decreased with age, 3. Proportion of OTU338 decreased in the subject group with high serum albumin level, 4. Proportion of OTU124 increased in the subject group with high rice intake, 5. Proportion of OTU919 and 124 increased in the subject group with high milk intake, 6. Proportion of OTU124 decreased in the subject group with high raw vegetable intake, 7. Proportion of OTU124 increased in the subject group with sleep disorder, 8.The relationship between proportion of OTU332 (lactobacillus) and body fat percentage - in 65+ -year-old females, significantly high percentage of OTU332 was observed in those with body fat percentage of less than 25% compared to those with greater than 25%. Thus, lactobacillus was suggested to have a preventive effect against obesity.

在普通人群中调查肠道菌群与一般健康状况之间的关系。得到以下结果：1. OTU657和990的比例随着年龄的增长而增加。OTU940的比例随着年龄的增长而下降。血清白蛋白水平高的受试者组OTU338比例降低；4 .高大米摄入组OTU124比例增加。5 .高牛奶摄入组OTU919和124的比例增加。生蔬菜摄入量高的受试者组OTU124比例下降；OTU124在有睡眠障碍的被试组中所占比例增加。OTU332（乳酸菌）的比例与体脂率的关系——在65岁以上的女性中，体脂率低于25%的女性OTU332的比例明显高于体脂率高于25%的女性。因此，乳酸菌被认为对肥胖有预防作用。

项目成果

腸内細菌とがん

肠道细菌与癌症

• 发表时间: 2012
• 期刊: 腫瘍プラクティス
• 作者: 中路重之;岩根かほり;辨野義己
• 通讯作者: 辨野義己

腸内の乳酸菌と肥満の関連について

关于肠道乳酸菌与肥胖的关系

• 发表时间: 2012
• 作者: Kumeta K;Danjo K;Matsuzaka M;Takahashi I;Watanabe K;Iwane K;Tsuya R;Umeda T;Sato K;Fukuda S;Nakaji S;渡邉 清誉,高橋一平,本田 勝義,米田 勝朗,三輪 孝士,和田 尚子,伊東 良,上谷英史,梅田 孝,中路 重之
• 通讯作者: 渡邉 清誉,高橋一平,本田 勝義,米田 勝朗,三輪 孝士,和田 尚子,伊東 良,上谷英史,梅田 孝,中路 重之

Knee osteoarthritis, knee joint pain and aging in relation to increasing serum hyaluronan level in the Japanese population

• DOI: 10.1016/j.joca.2010.10.021
• 发表时间: 2011-01-01
• 期刊: OSTEOARTHRITIS AND CARTILAGE
• 影响因子: 7
• 作者: Inoue, R.;Ishibashi, Y.;Toh, S.
• 通讯作者: Toh, S.

Prevelence of irritable bowel syndrome and its relation to lifestyle and depression quotient in a Japanese general population

日本普通人群肠易激综合征的患病率及其与生活方式和抑郁商数的关系

• 发表时间: 2011
• 期刊: Hirosaki Med J
• 作者: Kumeda K;Danjo K;Matsuzaka M;Takahashi I;Watanabe K;Iwane K;Tsuya R;Umeda T;Sato K;Fukuda S;Nakaji S
• 通讯作者: Nakaji S

Ankle brachial pressure index as a marker of apathy in a community dwelling population.

踝臂压力指数作为社区居住人群冷漠的标志。

• 发表时间: 2011
• 期刊: Int J Geriatr Psychiatry
• 作者: Sugawara N;Yasui-Furukori N;Umeda T;Kaneda A;Sato Y;Takahashi I;Matsuzaka M;Danjo K;Nakaji S;Kaneko S.
• 通讯作者: Kaneko S.