USEFULNESS OF LABORATORY HAIRLESS DOGS IN THE FIELD OF DERMATOSURGERY
USEFULNESS OF LABORATORY HAIRLESS DOGS IN THE FIELD OF DERMATOSURGERY
批准号:
11556059
负责人:
DOI Kunio
金额:
$8.51万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
1999
资助国家:
日本
项目状态:
已结题
起止时间:
1999 至 2001
中文摘要
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英文摘要
Usefulness of laboratory hairless dogs (LHDs) in the field of dermatosurgery was investigated. As a result, it was clarified that LHDs were useful as a burn wound or skin injury healing model and efficacy and safety of several kinds of wound dressings were examined using these models. In addition, it was shown that LHDs were useful for the evaluation of efficacies of Q-switched ruby laser irradiation and hydroquinone on senile spotty pigmentation. Moreover depigmentation and rejuvenation effects of all-trans-retioic acid and kinetin on senile dorsal skin of LHDs were investigated, suggesting a usefulness of LHDs in those experiments.Thus the usefulness of LHDs in the field of dermatosurgery was clarified.
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Kimura T. and Doi K.: "Effects of indomethacin on sunbum and suntan reactions in harless descendants of Mexican Hairless dogs"Histol. Histopathol. 13. 29-36 (1998)
Kimura T. 和 Doi K.:“吲哚美辛对墨西哥无毛狗无毛后代晒伤和晒黑反应的影响”Histol。
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Kimura T., Doi K.: "Dermatotoxicity due to wound dressing with chitosan and chitin in hairless dogs"Vet. Dermatol.. (in press). (2000)
Kimura T.,Doi K.:“无毛犬中使用壳聚糖和甲壳素进行伤口敷料导致的皮肤毒性”兽医。
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Kimura T., Doi K.: "Dermatotoxicity due to wound dressings with chitosan and chitin in hairless dogs"Vet. Dermatol.. (in press). (2002)
Kimura T.,Doi K.:“无毛犬中含有壳聚糖和甲壳素的伤口敷料引起的皮肤毒性”兽医。
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Kimura T., Doi K.: "Effects of all trans-retinoic acid on the dorsal skin of hairless dogs"Toxicol. Pathol.. Vol.26. 442-447 (1998)
Kimura T.,Doi K.:“所有反式视黄酸对无毛犬背部皮肤的影响”Toxicol。
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Kimura T. and Doi K.: "Dorsai skin reactions of hairless dogs to topical treatment with corticosteroids"Tox. Path.. 27. 528-535 (1999)
Kimura T. 和 Doi K.:“无毛狗对皮质类固醇局部治疗的 Dorsai 皮肤反应”Tox。
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共 15 条
Mechanisms of chemical-induced fetal brain toxicity
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批准号:13460139
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.6万
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财政年份:2001
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负责人:DOI Kunio
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依托单位:
ANALYSIS OF CHARACTERISTICS AND PATHOGENESIS OF SKIN INJURY INDUCED BY ENVIRONMENTAL CHEMICALS AND ULTRAVIOLET LIGHT
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批准号:10460139
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$7.23万
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财政年份:1998
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负责人:DOI Kunio
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依托单位:
USEFULNES OF LABORATORY HAIRLESS DOG IN THE DEVELOPMENT OF DERMAL MEDICINES AND COSMETICS
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批准号:08556049
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$6.34万
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财政年份:1996
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负责人:DOI Kunio
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依托单位:
MECHANISM OF GALACTOSAMINE-INDUCED HEPATOCYTE APOPTOSIS
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批准号:07456139
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.22万
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财政年份:1995
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负责人:DOI Kunio
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依托单位: