Development of Tele-Neuroendovascular Therapy Support System

1.利用超级计算机进行脑血管三维重建：该方法是在高分辨率3D-DSA获得数据的几小时内，利用超级计算机流体动力学分析开发的。2.应用于临床病例分析：对脑动脉瘤、动脉粥样硬化和动静脉瘘进行了分析，为治疗提供了有用的信息。重点分析了脑动脉瘤的发生、生长和破裂过程，并提出了一些具有血流动力学意义的线索。3.神经血管内治疗的虚拟现实仿真研究：利用PHANToM力反馈装置，实现了神经血管内治疗的虚拟仿真。原始的导丝操作模拟软件使我们能够使用这个虚拟现实系统进行训练，预先模拟真实的治疗等。4.未来的发展方向：随着虚拟现实系统的发展及其在训练中的应用，远程神经血管内治疗将成为现实。利用微型机器人技术开发各种类型的主从式系统势在必行。本研究结果将广泛应用于脑血管疾病的科学循证病理生理精细分析。

1.Three-dimensional reconstruction of brain vessels using super-computer: The method was developed using super-computer fluid dynamics analysis within few hours from data acquisition by high resolution 3D-DSA. Four dimensional analysis is now possible (3D with cardiac cycle into account).2.Application into clinical case analysis: Brain aneurysm, atherosclerosis and arterio-venous fistulas were analyzed with useful contribution for the treatment. Special attention was paid to analyze the initiation, growth and rupture of brain aneurysm and some hemodynamically significant clue was brought in.3.Development of virtual reality simulation of neuroendovascular therapy: Using PHANToM force-feed back device, it is now possible to simulate neuroendovascular therapy. Primitive guide wire mainipulation simulation software enabled us to use this virtual reality system for training, simulation beforehand the real treatment and so on.4.Future directions: Tele-Neuroendovascular therapy will be a reality with the development of virtual reality system and its application into training. It is mandatory to develop various types of master-slave system utilizing micro-robotics technology. The results of this research will be widely applied to the scientific evidence based pathophysilogical meticulous analysis of cerebrovascular diseases.