Surface Plasmon Resonance Instrument

表面等离子共振仪

• 批准号: 460284161
• 金额: --
• 依托单位: Rheinisch-Westfälische Technische Hochschule Aachen
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2021
• 资助国家: 德国
• 起止时间: 2020-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/460284161?language=en
• 关键词: Surface; Plasmon; Resonance; Instrument

Due to their high relevance in the human organism, many medical research techniques focus on the identification of proteins. Such proteins exert their function independently of each other, but form complex networks with other proteins or biomolecules. Understanding these interactions is crucial to understanding the (patho-) physiological role of the protein in question. More and more scientists of the Medical Faculty of the RWTH Aachen University are interested in using Surface plasmon resonance as readout parameter in their scientific projects. These Surface plasmon resonance systems can not only bring their research closer to clinical application, but are also very well suited as a hypothesis generating system to develop completely new projects.A considerable number of scientists, both from the Faculty of Medicine of the RWTH as well as from the Homburg cooperation partners of the SFB/TRR219, have expressed considerable need and interest in Surface plasmon resonance, especially in the context of the SFB/TRR219, including 5 departments with 15 scientific directors, which clearly shows how relevant this tool is for the members of the Faculty of Medicine to achieve their important research goals now and in the future.

由于蛋白质与人体组织的高度相关性，许多医学研究技术都集中在蛋白质的鉴定上。这些蛋白质彼此独立地发挥其功能，但与其他蛋白质或生物分子形成复杂的网络。理解这些相互作用对于理解所讨论的蛋白质的（病理）生理作用至关重要。越来越多的亚琛工业大学医学院的科学家对利用表面等离子体共振作为读出参数的研究项目感兴趣。这些表面等离子体共振系统不仅可以使他们的研究更接近临床应用，而且也非常适合作为一个假设生成系统来开发全新的项目。来自RWTH医学院以及SFB/TRR 219的洪堡合作伙伴的相当多的科学家都表达了对表面等离子体共振的相当大的需求和兴趣，特别是在SFB/TRR 219的背景下，包括5个部门，15名科学主任，这清楚地表明了这个工具对于医学院的成员实现他们现在和未来的重要研究目标是多么重要。