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Preparation of DNA films showing a large anisotropic conductivity

Preparation of DNA films showing a large anisotropic conductivity
具有大各向异性电导率的 DNA 薄膜的制备
批准号:
13450388
负责人:
OKAHATA Yoshio
金额:
$8.9万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2001
资助国家:
日本
项目状态:
已结题
起止时间:
2001 至 2002

项目摘要

项目成果

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中文摘要
翻译
本项目的目的是制备一种DNA定向薄膜,该薄膜沿薄膜中的DNA链显示出大的各向异性导电性。Dna被认为具有电子转移的能力,因为dna在堆叠的碱基对中有许多π电子。我们制备了DNA-脂膜,并测量了它们的电导率。在这项研究中,我们试图测量单个DNA分子作为纳米线的电导率。我们用Langmuir-Blodgett方法制备了DNA纳米线,并在荧光显微镜下观察到了排列的DNA纳米线。此外,还在交叉型微电路上测量了DNA纳米线的电子导电性。通过电导测量,我们发现DNA纳米线是良好的半导体材料(0.1-1s cm-1)。
英文摘要
The purpose of this project is to prepare a DNA aligned film that shows a large anisotropic conductivity along DNA strands in the film. DNA is believed to be having an ability of electron transfer, because DNA has many π-electrons within the stacked base pairs. We prepared DNA-lipid films and measured their conductivities. In this research, we tried to measure the conductivity of a single DNA molecule as a nanowire. We have prepared DNA-nanowires by using Langmuir-Blodgett method, and observed aligned DNA -nanowires by a fluorescent microscopy. Further, the electron conductivity of DNA-nanowires was also measured on an interdigitated microcuit. We found that DNA-nanowires are good semiconductor (0.1-1S cm-1) from conductivity measurements.
期刊论文(34)
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会议论文
H. Furusawa, Y. Kitamura, N. Hagiwara, T. Turimoto, and Y. Okahata: "Binding Kinetics of the Toroidal-Shaped PCNA to DNA Strands on a 27 MHz Quartz-Crystal Microbalance"Chem PhysChem.. No.5. 446-448 (2002)
H. Furusawa、Y. Kitamura、N. Hagiwara、T. Turimoto 和 Y. Okahata:“27 MHz 石英晶体微天平上环形 PCNA 与 DNA 链的结合动力学”Chem PhysChem.. No.5。
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通讯作者:
H.Furusawa, Y.Kitamura, N.Hagiwara, T.Turimoto, Y.Okahata: "Binding Kinetics of the Toroidal-Shaped PCNA to DNA Strands on a 27 MHz Quartz-Crystal Microbalance"ChemPhysChem.. No.5. 446-448 (2002)
H.Furusawa、Y.Kitamura、N.Hagiwara、T.Turimoto、Y.Okahata:“27 MHz 石英晶体微天平上环形 PCNA 与 DNA 链的结合动力学”ChemPhysChem.. No.5。
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通讯作者:
T.Fukushima, Y.Inoue, T.Hayakawa, K.Taniguchi, K.Miyazaki, Y.Okahata: "Preparation of and Tissue response to DNA-Lipid Films."J. Dental Res.. 80. 1772-1776 (2001)
T.Fukushima、Y.Inoue、T.Hayakawa、K.Taniguchi、K.Miyazaki、Y.Okahata:“DNA-脂质膜的制备和组织反应”。
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H. Matsuno and Y. Okahata: "Direct Monitoring of DNA Cleavages catalyzed by an ATP-dependent Deoxyribonuclease on a 27 MHz Quartz-Crystal Microbalance"Chem. Commun.. 470-471 (2002)
H. Matsuno 和 Y. Okahata:“在 27 MHz 石英晶体微天平上直接监测 ATP 依赖性脱氧核糖核酸酶催化的 DNA 裂解”Chem。
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12
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    • 批准号:
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    • 项目类别:
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    • 资助金额:
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    • 财政年份:
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    • 负责人:
      OKAHATA Yoshio
    • 依托单位:
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    • 资助金额:
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    • 项目类别:
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    • 资助金额:
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    • 财政年份:
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    • 负责人:
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    • 项目类别:
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    • 资助金额:
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    • 财政年份:
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    • 负责人:
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