Do electromagnetic fields including cellular phone make brain tumor? -Epidemiological study-

一些表皮病学研究表明，暴露在电磁场中会增加婴儿白血病的发病率。我们研究了暴露在电磁场中是否可以诱发染色体的异常。将新生大鼠及其星形胶质细胞暴露于10mT(50赫兹)的电磁场中7天。染毒组新生大鼠微核发生率明显升高。但经Ames检验无差异。为了弄清电磁场作业人员的影响，我们进行了流行病学研究。对工作人员(医学核磁共振学会S分会会员)和对照组进行问卷调查。工人和对照组的应答率分别为28%(864/3076)和14%(172/1213)。在性别分布方面，工人组男性为705人(88%)，对照组为100人(61%)。男性平均年龄为42.0±-7.9岁，女性为38.3±-8.2岁。对照组为42.5+/-11.8，28.4+/-5.9。为了解手机对大学生的影响，我们对104名医学生和128名工科大学生进行了调查。医科学生和工科学生的拥有率分别为98%和91%。我们调查了手机对健康的影响是否为肩部不适、恶心、头痛或听觉，并调查了8名主要工作人员的血液和尿液成分、日常生活时间表、5天内个人电磁场水平和工作场所电磁场水平。8名工人的性别仅为男性。8名工人的平均年龄和SD为34.8+/-14.2。血、尿主要检测项目为17-KS、17-uchS、皮质醇、褪黑素、乳酸脱氢酶、乳酸脱氢酶同工酶等。

It is supported by some epiderniological studies that the incidence of infantile leukemia increased by exposure to electromagnetic fields (EMFs). We investigate whether the chromosome aberration can be induced by exposure to EMFs. New born rats and their astrocytes were exposed to 10mT (50Hz) of EMFs for 7 days. The frequency of micronuclei in newborn rats of exposure group increased significantly. But there is no difference by Ames tests.In order to make clear the influence of the workers in EMFs we made epidemiological studies. We did questionnaire survey to the workers(members of J S of Magnetic Resonance in Medicine) and controls. Response rates of the workers and controls were 28 % (864/3076) and 14% (172/1213). For sex distributions males were 705(88%) for the workers and 100(61%) for controls. Mean age and SD of the workers were 42.0 +/-7.9 for male and 38.3 +/-8.2 for female. And those of controls were 42.5 +/-11.8, 28.4+/-5.9 as follows. We surveyed 104 medical and 128 engineering students to know influences of cellular phone. Ownership rates of that were 98% for medical and 91% for engineering students. We surveyed if effects of cellular phone to health were shoulder discomfort, nausea, headache or auditory sense.And we surveyed components of blood and urine, time tables of daily life, monitoring of EMFs level of individuals in 5 days and EMFs level of work space of the main 8 workers. Sex of 8 workers was male only. Mean age and SD of the 8 workers were 34.8 +/-14.2. Main items of blood and urine tests were 17-KS, 17-OHCS, cortisol, melatonin, LDH, LDH-isozyme and so on.