Biological effects of whole body exposure to static magnetic fields.

这项研究的目的是研究静磁场的生物效应。1)研究了4.7特斯拉(T)静磁场(SMF)对小鼠摄食量、摄食量和某些血清生化指标的影响。暴露48h后，食物、水摄入量和体重均有显著下降。4.7T SMF染毒后24小时小鼠肝脏苯胺脱氢酶活性显著升高，而3.0T SMF对小鼠肝脏苯胺脱氢酶活性无明显影响。4)4.7T SMF对小鼠肝脏自由基产生无明显影响。已知的是，四氯化碳(CCl_4)也能诱导组织中的自由基。5)4.7T SMF还能诱导小鼠肝脏金属硫蛋白的生成。6)4.7T SMF对哺乳动物培养细胞微核的诱发作用在4.7T SMF暴露48h后增加。

The aim of this studies is to investigate a biological effects of static magnetic fields. The following results were obtained for 2 years investigation.1) The effects of 4.7 tesla (T) static magnetic fields (SMF) on food and water intake and some serum biochemical parameters in mice were examined. Food and water intake and body weight decreased statistically after 48 h of exposure. The blood urine nitrogen and blood glucose levels increased significantly after 48h of exposure.2) Enzyme activity of aniline dehydrogenase in mouse liver increased significantly 24h after exposure to 4.7T SMF,but not 3.0T SMF.3) No significant effect of enzyme activity in mouse liver treated with 7,12- dimethylbenzanthracene was observed after exposure to SMF.4) 4.7T SMF influences the production of free radicals in mouse liver. It is known that carbontetrachloride (CCl_4) also induces the free radical in tissues. Then, combination exposure of CCl_4 and SMF enhances the production of free radicals in liver of mice than exposure of them separately.5) 4.7T SMF also induces metallothionein in liver of mice.6) Induction of micronuclei induced by mitomycin C in mammalian cultured cells was increased 48h exposure to 4.7T SMF.7) Mutagenic effects of spot-test using Drosophila melanogaster were observed by SMF and low frequency magnetic fields.