Two dimensional crystallization of ferritin protein for nano-scale process in semiconductor fabrication

Development of biotechnology has been remarkable，which enables us to fabricate nanoscale structures using biomolecules as nanoblocks. A combination生物技术和半导体技术是一种promising candidate for enabling abreakthrough in the fabrication of advanced electronic devices. the main features of biotechnologyfrom a nanotechnology point of view are as follows：Size distribution is extremely small on the molecular scale. Biomolecules can form nanostructures ina self-assembling manner，这是一种基础制造技术（bottom-up fabrication technology）。biomineralize inorganic materials at its surface. Utilizing these characteristics我们提供一个novel bottom-up method for fabricating nanostructure with a very small sizedistribution.We have a floating nano-dot gate metal-oxide-semiconductor field effecttransistor . The floating nano-dots gate MOSFET是expected to be promising candidate组件for next-generation memory such as flash memory.它是必需的floatingnanod-dots have a small size distribution and should take the form of a high-density monolayer. We采用cage-shaped protein ferritin to satisfy这些要求。ferritin has a proteinshell, its outer and inner diameters are 12 nm and 7 nm, respectively，这是fairly high thermal and pH stabilities compared with其他proteins. The inner cavity canaccommodate an iron oxide core (5fe_2o_3 / 9h_2o). Therefore，iron oxide nano-dots with small size distribution can be artificially synthesized with ferritin这也可以解释ferritin molecules可以形成一个大的两种不同的crystala high-density monolayer. Combining these characteristics我们构造一个monolayer of ferritin with iron oxide cores。

Development of biotechnology has been remarkable, which enables us to fabricate nanoscale structures using biomolecules as nanoblocks. A combination of biotechnology and semiconductor technology is emerging as a promising candidate for enabling a breakthrough in the fabrication of advanced electronic devices. The main features of biotechnology from a nanotechnology point of view are as follows : Size distribution is extremely small on the molecular scale. Biomolecules can form nanostructures in a self-assembling manner, which is an essential part of the bottom-up fabrication technology. Protein has the ability to biomineralize inorganic materials at its surface. Utilizing these characteristics, we propose a novel bottom-up method for fabricating nanostructure with a very small size distribution.We have a floating nano-dot gate metal-oxide-semiconductor field effect transistor(MOSFET). The floating nano-dots gate MOSFET is expected to be promising candidate component for next-generation memory such as flash memory. It is required that the floating nanod-dots have a small size distribution and should take the form of a high-density monolayer. We adopted the cage-shaped protein ferritin to satisfy these requirements. Ferritin has a protein shell, its outer and inner diameters are 12 nm and 7 nm, respectively, and it has fairly high thermal and pH stabilities compared with other proteins. The inner cavity can accommodate an iron oxide core (5Fe_2O_3・9H_2O). Therefore, iron oxide nano-dots with small size distribution can be artificially synthesized with ferritin molecules. It has also demonstrated that ferritin molecules can form a large two-dimensional crystal that is a high-density monolayer. Combining these characteristics, we fabricated a monolayer of ferritin with iron oxide cores.