Multi purpose chemical sensor detecting substructure of molecules

检测分子子结构的多用途化学传感器

• 批准号: 15550124
• 负责人: HAYASHI Kenshi
• 金额: $ 2.43万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2004
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15550124/
• 关键词: Surface polarization control; Electrochemical impedance; CPE characteristics; Surface characterization; Surface monolayer; Molecular imprinting; センサ; 分子認識; 部分構造; 味; 匂い

Adsorbing molecules on surfaces deveoped here were characterized using electrochemical impedance measurement under dynamic potential scan. CPE(constant phase element) impedance is altered by roughness and inhomogeneity of the adsorbing surface in atomic scale. Consequently, the impedance includes information about adsorbing molecular substructures. On the other hand, interaction between surface and adsorbing molecules is modified by means of potential scan. Thus, the impedance profiles by surface electrical polarization can be used for sensor output which contains molecular information about adsorbates.Instrumental surface characterizing methods were also carried out on the surface. ESCA and AFM gave information about adsorbing chemicals. The characterization also provides knowledge about design of the sensor surface.Investigated sensor surface was modified chemically using SAMs (self assembled monolayer). Simple molecular imprinting was used on fabrication of SAMs surface to get specificity to target chemical substructure. Such functionalized surface had sensitivity to aromatic or alcoholic substances.Consequently, measured chemicals could be categorized into there substructures. The information about molecular substructures relates to odor code, which can be used for evaluation of odor quality. The developed sensor also works as a simple method for analytical chemistry, which can realizes grouping of chemicals using the information about molecular substructure.

使用动态电位扫描下的电化学阻抗测量来表征此处开发的表面上的吸附分子。 CPE（恒相元件）阻抗会因原子尺度上吸附表面的粗糙度和不均匀性而改变。因此，阻抗包括有关吸附分子子结构的信息。另一方面，通过电位扫描来改变表面和吸附分子之间的相互作用。因此，表面电极化的阻抗分布可用于传感器输出，其中包含有关吸附物的分子信息。还在表面上进行了仪器表面表征方法。 ESCA 和 AFM 提供了有关吸附化学品的信息。表征还提供了有关传感器表面设计的知识。研究的传感器表面使用 SAM（自组装单层）进行化学修饰。简单的分子印迹用于制造 SAM 表面，以获得目标化学子结构的特异性。这种功能化表面对芳香族或酒精类物质敏感。因此，测量的化学物质可以分为这些子结构。分子亚结构的信息与气味代码相关，可用于气味质量的评价。所开发的传感器还可以作为分析化学的一种简单方法，可以利用分子子结构的信息实现化学物质的分组。

项目成果

Detection of the Partial Structure of Odor Molecules by Self-Assembled Monolayers and Polarity Control of the Surface

自组装单分子层检测气味分子的部分结构和表面极性控制

• 发表时间: 2004
• 期刊: Chemical Sensors 20
• 作者: H.Yoshino;K.Murata;K.Saito;H.Nishikawa;K.Kikuchi;I.Ikemoto;K.Masunaga et al.;H.Nishikawa et al.;R.Izumi et al.
• 通讯作者: R.Izumi et al.

R.Izumi, M.Iwakura, K.Hayashi, K.Toko: "Detection of odorants trapped on a water membrane using surface-polarity controlled sensor"Proceeding of ISEE2003. 530-533 (2003)

R.Izumi、M.Iwakura、K.Hayashi、K.Toko：“使用表面极性控制传感器检测水膜上截留的气味剂”ISEE2003 论文集。

表面分極制御法による水道水汚染物質の検出

表面偏振控制法检测自来水污染物

• 发表时间: 2005
• 期刊: 電気学会論文誌E 125・2
• 作者: K.Yokoyama;H.Nishikawa;K.Kikuchi;T.Kodama;I.Ikemoto;J.Yamada;林 健司 他
• 通讯作者: 林 健司 他

K.Hayama, K.Hayashi, K.Toko: "Development of the electrochemical quantitative and qualitative analysis for adsorbates on Pt electrodes"Proceeding of ISEE2003. 416-419 (2003)

K.Hayama、K.Hayashi、K.Toko：“Pt 电极吸附物电化学定量和定性分析的发展”ISEE2003 论文集。

Detection of Water Pollutant Using Surface-Polarity Controlled Sensor

使用表面极性控制传感器检测水污染物

• 发表时间: 2005
• 期刊: IEEJ Trans.SM Vol.125, No.2
• 作者: K.Kikuchi;H.Nishikawa;T.Morimoto;T.Kodama;I.Ikemoto;J.Yamada;K.Hayashi et al.
• 通讯作者: K.Hayashi et al.