Development of Label-Free Electrochemical Impedance Biosensors for Surveillance of the Immune Response

该项目的目的是研究EIS生物传感的新用途，用于高度选择性地测定炎症免疫生物标志物（如细胞因子和其他炎症介质），并评估其在通过体外装置包埋水疱渗出液中评估免疫反应的适用性。研究将集中在使用电化学阻抗谱实时监测炎症免疫反应及其适用性来研究组织液和感兴趣的化合物之间的动态相互作用。

The aim of this project is to investigate the novel use EIS biosensing for highly selective determination of inflammo-immune biomarkers (e.g. cytokines and other inflammatory mediators) and to assess its applicability for the evaluation of the immune response in blister exudate fluid via inclusion in an extracorporeal device. Research will focus on use of electrochemical impedance spectroscopy for real-time monitoring of the inflammo-immune response and its applicability to investigate the dynamic interaction between tissue fluid and compounds of interest.