Development of Label-Free Electrochemical Impedance Biosensors for Surveillance of the Immune Response

开发用于监测免疫反应的无标记电化学阻抗生物传感器

• 批准号: 2415270
• 金额: --
• 依托单位: University College London
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2415270
• 关键词: Development; Label; Free; Electrochemical; Impedance

The aim of this project is to investigate the novel use EIS biosensing for highly selective determination of inflammo-immune biomarkers (e.g. cytokines and other inflammatory mediators) and to assess its applicability for the evaluation of the immune response in blister exudate fluid via inclusion in an extracorporeal device. Research will focus on use of electrochemical impedance spectroscopy for real-time monitoring of the inflammo-immune response and its applicability to investigate the dynamic interaction between tissue fluid and compounds of interest.

本项目的目的是研究EIS生物传感的新用途，用于高度选择性测定炎症免疫生物标志物（例如细胞因子和其他炎症介质），并评估其通过纳入体外装置评价水疱渗出液中免疫反应的适用性。研究将侧重于使用电化学阻抗谱实时监测炎症免疫反应及其适用性，以调查组织液和感兴趣的化合物之间的动态相互作用。