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Application of Spectral Imaging Technology to a New Non-invasive Visual Diagnostic Method

光谱成像技术在新型无创视觉诊断方法中的应用

基本信息

批准号：
15590480
负责人：
NISHIBORI Masahiro
金额：
$ 2.24万
依托单位：
Tokyo Medical and Dental University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2004
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15590480/
关键词：
spectral reflectance spectral estimation color reproduction real color picture medical imaging estimation of pigmnt distribution multispectral imaging device-illuminant independence

项目摘要

A system of illuminant-independent color reproduction has been developed for practical use in medicine, and its performance was subjectively evaluated by a group of healthcare professionals of various specialties. For medical diagnosis, it is important to archive image data of diseased skin for the purpose of visually reviewing its chronological changes. However, sufficient color reproduction quality has never developed for this purpose. First, the illuminant conditions at various locations in a university hospital were measured and it was found that illuminants used in the hospital have a wide range of colors and that some of them have color rendering index (Ra) values that are too low for ordinary colorimetric color reproduction. Therefore, the multi-spectral imaging technique was applied for the illuminant-independent color reproduction to correct the color adaptively to the various kinds of illuminant. The healthcare professionals group evaluated the reproduced skin color by comparing the images with real skin. The results verify the effectiveness of the developed system and also expose the medical need for shading reproduction in addition to averaged color reproduction.After that, a prototype system was developed. That system translates color of skin captured by an ordinary three band camera to that of an actual one regardless of the illuminating conditions and simultaneously visualizes distribution of melanin, hemoglobin and oxyhemoglobin in real time. It will be expected to inspire a wide range of research activities for medical application.

已经开发了一种用于医学实际用途的独立于光源的颜色再现系统，并且由一组不同专业的医疗保健专业人员对其性能进行了主观评估。对于医学诊断，重要的是将患病皮肤的图像数据存档，以便在视觉上查看其时间变化。然而，从未为此目的开发出足够的颜色再现质量。首先，测量了大学医院中各个位置的光源条件，发现医院中使用的光源具有广泛的颜色范围，并且其中一些光源的显色指数（Ra）值对于普通的比色颜色再现来说太低。因此，多光谱成像技术被应用于光源无关的颜色再现，以适应各种光源的颜色校正。医疗保健专业人员组通过将图像与真实的皮肤进行比较来评估再现的皮肤颜色。实验结果验证了所开发系统的有效性，同时也揭示了医学上除了平均色彩再现外，对阴影再现的需求。该系统将由普通三波段相机捕获的皮肤颜色转换为实际的颜色，而不管照明条件如何，并且同时真实的可视化黑色素、血红蛋白和氧合血红蛋白的分布。预计它将激发广泛的医学应用研究活动。