Research on circadian variations of biological variables, such as blood pressure, body temperature, etc. in different sleep-wake patterns III.

为了研究生物变量昼夜节律变化的变化，2003年，14名学生(10名男性，4名女性)在受控的身体条件和生活环境下进行了连续72小时的研究。睡眠时间：第1天00：00~07：00，第2天零，第3天12：00~19：00。观察男性血压、脉率及血、尿生化和内分泌指标。我们已经报道过，昼夜节律变化对睡眠-醒来时间表的调整发生在不同的变量和受试者的不同速率上。这一次，我们一起研究了女性。变量的昼夜变化在两性中显示出几乎相同的模式，但中层不同。然而，在某些变量上，女性表现出比男性更高的幅度。我们首次研究的尿褪黑激素排泄量在睡眠改变后变化缓慢。对相移的反应也因人而异。我们调查了春夏两季大学生的日常生活时间。我们还报告说，在节假日，他们醒得比平时晚，而且那些不吃早餐的人比吃早饭的人醒得晚得多。这一次我们在冬季进行了调查。它们的日常生活时间不随季节变化，但雌性和雄性的时间不同，主要是因为吃早餐。

To investigate the changes revealed in circadian variations of biological variables, when a sleep phase was shifted, fourteen students (ten males, four females) were studied for 72 hours continuously under a controlled physical conditions and living environment in 2003. Sleep hours were from 00:00 to 07:00 on the 1st day, zero on the 2nd day, and from 12:00 to 19:00 on the 3rd day.We had studied blood pressure, pulse rate, and biochemical and endocrinological variables in blood and urine in males. And we had reported that adjustment of circadian variations to changed sleep-wake schedules occurred at different rates by variable and also by subject.This time we studied females together. Circadian variations of variables showed almost same patterns in both genders, with different mesors. However, in some variables females showed higher amplitudes than in males.Urinary melatonin excretion, that we studied for the first time, shifted slowly after the shifted sleep. The reactions to the phase shift also depended on persons.We had surveyed timings of daily life in university students during Spring to Summer seasons. And we reported that on holidays they woke up later than on weekdays, and that those who did not eat breakfast woke up much more later than those who had breakfast. This time we conducted surveys during Winter. Their timings of daily life did not change between seasons, however, timings in females were different to males, mainly, due to eating of breakfast.