Liver atrophy and Lipid metabolism after mesocaval and portocaval shunt in the rats

外科内脏循环转流进入体循环，如下腔静脉后分流术或下腔静脉系分流术，在肝移植的当今时代仍有报道用于治疗门静脉高压症引起的食管静脉曲张出血。即使在肝移植受者中，外科门体分流术也被证明可以成功缓解门静脉高压，并且为了避免在使用小尺寸部分肝移植的成人受者中因过度灌注而导致的移植物充血和失败。当有内在性肝病的患者需要进行门体分流术时，必须考虑将来肝移植的可能性。然而，在肝移植受者中，只要没有发生肝性脑病，外科分流就不能关闭。肠腔分流组的体重与对照组相比没有显著减少。而肠腔分流组肝重增加较对照组明显减少。肠腔分流术组甘油三酯分泌率明显低于对照组。肠腔分流道甘油三酯分泌率与肝重显著相关。

Surgical splanchnic circulatory diversion into the systemic circulation, such as posrtocaval shunting or mesocaval shunting, has still been reported to treat bleeding esophageal varices caused by portal hypertension in the present era of liver transplantation. Even in liver transplanted recipients, surgical portosystemic shunting has been indicated to alleviate successfully portal hypertension, and in order to avoid graft congestion and failure by overperfusion in adult recipients using small-for-size partial liver graft. When a surgical portosystemic shunting is necessary in a patient with intrinsic liver disease, the possibility of future liver transplantation has to be considered. In liver transplanted recipients, however, surgical shunt cannot be closed whenever hepatic encephalopathy does not develop.Body weight of mesocaval shunt group did not significantly less increase in comparison with control group. While, liver weight of mesocaval shunt significantly less increased in comparison with control group. Triglyceride secretion rate of mesocaval shunt significalntly less increased in comparison with control group. Triglyceride secretion rate of mesocaval shunt significantly correlated with liver weight.