THE EFFECT OF ADENOSINE METABOLISM ON THE EXPRESSION OF P-SLECTIN IN POSTMENOPAUSAL WOMEN.

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[PURPOSE]The purpose of this study is to evaluate the relationship between adenosine and P-selectin, platelet activation marker in menopausal women,[METHOD]We measured plasma adenosine and the expression of P-selectin by flowcytometry,in menopausal women, and then evaluate the relationship between them.[RESULTS]The reduction of plasma adenosine in menopausal women nay be associated with the inrease in the the expression of P-selectin in menopausal women,[CONCLUSION]This study has suggested that plasma adenosine may play role in the regulation of P-selecin, which eventually dampens to worsen the atherosclerosis in menopausal women.