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Differences of bone and microvasculature around implant with different surface treatment under occlusal function

不同表面处理的种植体周围骨及微血管在咬合功能下的差异

基本信息

批准号：
15592088
负责人：
IKE Hiromi
金额：
$ 2.18万
依托单位：
Osaka Dental University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2004
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15592088/
关键词：
Dental implant Surface treatment Occlusal function Microvascularization Osteogenesis SEM 微細血管構築

项目摘要

It is necessary that implantal alveolar bone(IB) and bone trabeculare(BT) keep being maintained under occlusal function. However, it is thought that reaction of both bones and microvasculature differs by difference of implant surface treatment. Three kind of implant with different surface treatments were installed in superstructures and they functioned under occlusion for 1,2,4,8,12 or 24 weeks. Changes of both bones and microvasculature under occlusal function were investigated with SEM. Three kinds of implants are as follows.Blast processed implant(Blast) Blast unprocessed implant(N-Blast) Hydroxyapatite coated implant(HAC)IB and BT in Blast were the thinnest in three kinds of implants in each period under function. It is suggested that Blast will not be supported with thick IB and fat BT under function, because thin IB, a thin BT, and partial lack of both bone were observed in 24 week. It is thought that N-Blast will be supported with thick TB and thin BT for a long term under function, because remarkable changes of both bone did not be observed during function. In HAC, osteogenesis continued in both bone 1-8 week after function, both bone were absorbed rapidly in 12 week, and HAC was supported with the bones which were almost similar to those of N-Blast in 24 week. Because remarkable changes in both bone of N-Blast and HAG were not observed 12-24 week, it is thought that both bone of N-Blast and HAC will be maintained for a long term.Microvasculature was comparatively abundant in Blast, and comparatively few in N-Blast under function.This shows that neither osteogenesis nor resorption of bone happen easily. In HAG, Microvasculature changed according to increased or decreased of bone.It could be concluded that changes of bone formation and macrovasculature under occlusal function were different according to implant surface treatment.

种植牙槽骨（IB）和骨小梁（BT）在咬合功能下的持续维持是必要的。然而，由于种植体表面处理的不同，骨和微血管的反应也不同。将三种不同表面处理方式的种植体安装在上肢结构上，分别在咬合条件下运行1、2、4、8、12、24周。用扫描电镜观察了咬合功能对两组骨和微血管的影响。以下是三种植入物。Blast处理过的种植体（Blast） Blast未处理过的种植体（N-Blast）羟基磷灰石包覆种植体（HAC） Blast处理过的IB和BT是三种种植体中各时期最薄的。提示在正常功能下，厚的IB和厚的BT不能支持Blast，因为在24周时观察到薄的IB和薄的BT，并且两种骨都部分缺失。我们认为N-Blast在功能下将长期由厚TB和薄BT支撑，因为在功能期间没有观察到两种骨的显著变化。在HAC中，功能恢复后1-8周，两骨均继续成骨，12周时两骨吸收迅速，24周时HAC有骨支撑，与N-Blast基本相似。由于12-24周未观察到N-Blast和HAG骨的显著变化，因此认为N-Blast和HAC骨将长期维持。在功能状态下，Blast的微血管相对丰富，而N-Blast的微血管相对较少。这表明成骨和骨吸收都不容易发生。在HAG中，微血管随骨量的增加或减少而改变。可见，不同种植体表面处理对牙合功能下骨形成和大血管系统的影响不同。