Development of an ultrasonic device to detect early demineralized lesions and establishment of clinical criteria for these diagnoses
开发超声波装置来检测早期脱矿病变并建立这些诊断的临床标准
基本信息
- 批准号:15592212
- 负责人:
- 金额:$ 2.05万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2003
- 资助国家:日本
- 起止时间:2003 至 2004
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The onset of dental caries is characterized by white-spots or staining on tooth surfaces. However, estimation of caries activities of these lesions is difficult because we have no tool for recognition which lesion is demineralizing, arresting or re-mineralizing. For detection of the initial changes of the tooth surface affected by dental caries on the enamel and root, we developed a noninvasive, nondestructive dental explorer employing ultrasonic sensor technology. The ultrasonic sensor detection system consists of an oscillating piezoelectric element for sensing, a piezoelectric detective element to obtain frequency characteristics of the tooth surface, and a lightweight arm for positioning the sensor on the tooth surface. Extracted teeth were collected with informed consent and demineralized enamel specimens were prepared with lactate-CMC gel (6%, pH 4.5). The ultrasonic sensor was loaded on these tooth surfaces and scanned for drawing a map of the frequency characteristics. The surface characteristics were represented by the frequency shifts of oscillation in the resonance method. The detecting element of the developed ultrasonic sensor was sufficiently small in the clinic. By measurements using four sets of enamel specimens, early lesions of enamel caries were dearly represented by low frequency shifts of oscillation in a demineralized time-dependent manner. By scanning surfaces of ten extracted teeth, this detection system was able to distinguish sound or caries lesions on the enamel and roots, calculus depositions, staining, white spots and cracks on the enamel surface. However, additional information was need when exploring complex surfaces with overlapping lesions. Our new sensory explorer employing the ultrasonic resonance method was found to be a powerful tool for estimating initial change and degree of progression of dental caries.
龋齿的发病特征在于牙齿表面上的白点或染色。然而,估计这些病变的龋齿活动是困难的,因为我们没有工具来识别哪些病变是脱矿,阻止或再矿化。为了检测牙釉质和牙根受龋齿影响的牙齿表面的初始变化,我们开发了一种采用超声波传感器技术的非侵入性、非破坏性牙科探测器。超声波传感器检测系统由用于传感的振荡压电元件、用于获得齿面频率特性的压电检测元件和用于将传感器定位在齿面上的轻质臂组成。在知情同意的情况下收集拔牙,用乳酸盐-CMC凝胶(6%,pH 4.5)制备脱矿牙釉质样本。将超声波传感器加载在这些齿面上并扫描以绘制频率特性图。在共振法中,表面特性由振荡的频移来表示。所研制的超声传感器的检测元件在临床上是足够小的。通过使用四组牙釉质样本进行测量,牙釉质龋的早期病变可以通过脱矿时间依赖性的低频振荡变化来清楚地代表。通过对10颗离体牙的表面扫描,该检测系统能够区分牙釉质和牙根上的健全或龋齿病变、牙结石沉积、牙釉质表面的染色、白色斑点和裂纹。然而,当探索具有重叠病变的复杂表面时,需要额外的信息。我们的新感官探险家采用超声波共振方法被发现是一个强大的工具,估计初始变化和发展程度的龋齿。
项目成果
期刊论文数量(36)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Yamamoto E, Awano S, Koseki T, Ansai T, Takehara T.: "Expression of endothelin-1 in gingival epithelial cells."J Periodontal Res. 38・4. 417-421 (2003)
Yamamoto E、Awano S、Koseki T、Ansai T、Takehara T.:“牙龈上皮细胞中内皮素-1 的表达”。J 牙周研究 38・4(2003)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Involvement of caspase activation through release of cytochrome c from mitochondria in apoptotic cell death of macrophages infected with Actinobacillus actinomycetemcomitans.
- DOI:10.2504/kds.58.60_2
- 发表时间:2004-04
- 期刊:
- 影响因子:2.1
- 作者:Hironori Kasai;Kozo Yamamoto;T. Koseki;M. Yokota;T. Nishihara
- 通讯作者:Hironori Kasai;Kozo Yamamoto;T. Koseki;M. Yokota;T. Nishihara
Detection of subgingival calculus and dentine caries by laser fluorescence
激光荧光检测龈下牙石和牙本质龋齿
- DOI:
- 发表时间:2004
- 期刊:
- 影响因子:0
- 作者:Kurihara E;et al.
- 通讯作者:et al.
Growth/differentiation factor-5 induces growth arrest and apoptosis in mouse B lineage cells with modulation by Smad
- DOI:10.1016/s0898-6568(02)00088-8
- 发表时间:2003-02-01
- 期刊:
- 影响因子:4.8
- 作者:Nakahara, T;Tominaga, K;Nishihara, T
- 通讯作者:Nishihara, T
Gamma-interferon enhances expression of CD14/MyD88 and subsequent responsiveness to lipopolysaccharide from Actinobacillus actinomycetemcomitans in human gingival fibroblasts.
γ-干扰素增强人牙龈成纤维细胞中 CD14/MyD88 的表达以及随后对伴放线放线杆菌脂多糖的反应性。
- DOI:
- 发表时间:2004
- 期刊:
- 影响因子:0
- 作者:Mochizuki S;Kobayashi M;Suzuki T;Oikawa A;Koseki T;Nishihara T;Hasegawa K.
- 通讯作者:Hasegawa K.
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KOSEKI Takeyoshi其他文献
KOSEKI Takeyoshi的其他文献
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{{ truncateString('KOSEKI Takeyoshi', 18)}}的其他基金
Development of new evaluation system of mucosal inflammation based upon vascular imaging and preventive method of oral mucositis with oral mucosa mapping system
基于血管成像的新型粘膜炎症评估系统的开发及口腔粘膜标测系统预防口腔粘膜炎的方法
- 批准号:
26293440 - 财政年份:2014
- 资助金额:
$ 2.05万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Development of artificial saliva-secreting automated device placed inside the mouth activated by oral environment and functional activities
开发放置在口腔内由口腔环境和功能活动激活的人工唾液分泌自动化装置
- 批准号:
25670889 - 财政年份:2013
- 资助金额:
$ 2.05万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Clinical application of assessment devices for the risk of dental caries with ultrasonic haptic sensor technology
超声波触觉传感器技术龋齿风险评估装置的临床应用
- 批准号:
23659962 - 财政年份:2011
- 资助金额:
$ 2.05万 - 项目类别:
Grant-in-Aid for Challenging Exploratory Research
Development and proposal of evaluation method of oral mucosal damages based on the degree of injuries and atrophy of oral mucosa and saliva properties
基于口腔粘膜损伤、萎缩程度和唾液特性的口腔粘膜损伤评估方法的开发和提出
- 批准号:
23390479 - 财政年份:2011
- 资助金额:
$ 2.05万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Development of accelerated remineralization method based upon the non-invasive assessment of mineral density of tooth
基于牙齿矿物质密度无创评估的加速再矿化方法的开发
- 批准号:
20390532 - 财政年份:2008
- 资助金额:
$ 2.05万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Development of prevention method of periodontal diseases by understanding the mechanisms of intracellular invasion by periodontopathic bacteria
了解牙周病细菌侵入细胞内的机制,开发牙周病的预防方法
- 批准号:
13671932 - 财政年份:2001
- 资助金额:
$ 2.05万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Analysis of Destruction Mechanisms of Dental Biofilm by Laser and Its Clinical Application
激光破坏牙齿生物膜的机制分析及临床应用
- 批准号:
12557196 - 财政年份:2000
- 资助金额:
$ 2.05万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
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Design optimisation of ultrasonic hydrophones with inconsistent crossover calibrations
交叉校准不一致的超声波水听器的设计优化
- 批准号:
10089275 - 财政年份:2024
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$ 2.05万 - 项目类别:
Collaborative R&D
Collaborative Research:CIF:Small:Acoustic-Optic Vision - Combining Ultrasonic Sonars with Visible Sensors for Robust Machine Perception
合作研究:CIF:Small:声光视觉 - 将超声波声纳与可见传感器相结合,实现强大的机器感知
- 批准号:
2326905 - 财政年份:2024
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$ 2.05万 - 项目类别:
Standard Grant
Collaborative Research:CIF:Small: Acoustic-Optic Vision - Combining Ultrasonic Sonars with Visible Sensors for Robust Machine Perception
合作研究:CIF:Small:声光视觉 - 将超声波声纳与可见传感器相结合,实现强大的机器感知
- 批准号:
2326904 - 财政年份:2024
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$ 2.05万 - 项目类别:
Standard Grant
CBET-EPSRC Sustainable bioplastics prepared by ultrasonic treatment with low CO2 footprint
CBET-EPSRC 通过超声波处理制备的可持续生物塑料,二氧化碳足迹低
- 批准号:
EP/X039773/1 - 财政年份:2024
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Scalable Manufacturing of Nanobubbles via Ultrasonic Shearing for Biomedicine
通过超声波剪切大规模制造生物医学纳米气泡
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2322488 - 财政年份:2024
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Laboratory devise for the production of metallic and intermediate powders by ultrasonic atomisation
通过超声波雾化生产金属和中间粉末的实验室座右铭
- 批准号:
515508485 - 财政年份:2023
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Improving Ultrasonic Imaging using Machine Learning
使用机器学习改进超声成像
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基于人工智能的超声波阵列检测腐蚀和不平坦表面上的表面破裂缺陷
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2887816 - 财政年份:2023
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