Molecular Mechanism of Insect Metamorphosis and Diapause

昆虫变态和滞育的分子机制

• 批准号: 08276103
• 负责人: YAMASHITA Okitsugu
• 金额: $ 52.86万
• 依托单位: NAGOYA UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research on Priority Areas
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-08276103/
• 关键词: insect; metamorphosis; diapause; hormone; neurosecretion; non-self recognition; gene expression; environmental response; 神経ペプチドホルモン; ホルモン受容体; ペプチドホルモン; プロテアーゼ; 生体防御; 分子認識; 再生; 幼若ホルモン; 受容体

The research project "Molecular Mechanism of Insect Metamorphosis and Diapause" (abbreviated as metamorphosis and diapause mechanism) was conducted for 4 years from 1996 to 1999 by 62 scientists in various fields. This project took aim at the molecular analysis of metamorphosis and diapause of insects that are the essential events supporting the prosperity of insects in this planet. Toward this goal research proposals employing molecular genetics, biochemical analysis, cellular biology and environmental physiology were encouraged, and large members of new genes and components responsible for synthesis of neuropeptide hormone, for its action, for non-self recognition of larval tissues, for social differentiation of honey bees and for environmental response. Part of research achievements was made public in an open symposium ; "University and Sciences" organized by the Ministry of Education, Science, Sports and Culture. Core members of this project have examined and summarized the results obtained by research members. Thc outline of the results has been presented to the authority for the final evaluation of research activity. Finally, the research activity of this project was collectively compiled to the booklet to distribute to a large number of scientists, specialists and offices in the related field.

“昆虫变态和滞育的分子机制”（简称“变态和滞育机制”）是由62名各领域的科学家从1996年到1999年历时4年进行的研究项目。该项目旨在对昆虫的变态和滞育进行分子分析，这是支持地球上昆虫繁荣的重要事件。为了实现这一目标，鼓励采用分子遗传学，生化分析，细胞生物学和环境生理学的研究建议，以及负责神经肽激素合成，其作用，幼虫组织的非自我识别，蜜蜂的社会分化和环境反应的大量新基因和成分。部分研究成果以公开研讨会形式对外公布；由教育、科学、体育和文化部主办的“大学与科学”。本项目核心成员对研究成员取得的成果进行了审查和总结。结果大纲已提交给权威机构，以便对研究活动进行最终评估。最后，这个项目的研究活动被集体汇编成小册子，分发给有关领域的大批科学家、专家和办事处。

项目成果

S. D. Ha: "Isolation and structure determination of a paralytic peptide from the hemolymph of Bombyx mori"Peptides. 20. 561 (1999)

S.D.Ha：“家蚕血淋巴中麻痹肽的分离和结构测定”肽。

K.Ohashi et al.: "Change in the mode of gene expression of the hypopharyngeal gland cells with an age-dependent role change of the worker honeybee Apis mellifera L." Eur.J.Biochem.249. 797-802 (1997)

K.Ohashi 等人：“下咽腺细胞基因表达模式的变化与工蜂 Apis mellifera L 的年龄依赖性角色变化有关。”

Niimi,T.et al.: "Structure of the Bombyx sorbitol dehydrogenease gene : a possible alternative use of the promoter." Insect Molec.Biol.5. 269-280 (1996)

Niimi,T.et al.：“家蚕山梨醇脱氢酶基因的结构：启动子的一种可能的替代用途。”

Yanashita,O.: "Diapause hormone of the silkworm,Bombyx mori : structure,gene expression and function." J.Insect Physiol.42. 669-679 (1996)

Yanashita,O.：“家蚕滞育激素：结构、基因表达和功能。”

S. G. Dedos: "Differences between recombinant PTTH and crude brain extracts in cAMP-mediated ecdysteroid secreation from the prothoracic glands of the silkworm, Bomyx mori"J. Insect Physiol.. 45. 415-422 (1999)

S. G. Dedos：“重组 PTTH 和粗脑提取物在 cAMP 介导的家蚕前胸腺分泌蜕皮类固醇方面的差异”J.