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Association of retinal antigen Brn 3b with pathogenesis of Behcet's disease

Association of retinal antigen Brn 3b with pathogenesis of Behcet's disease
视网膜抗原Brn 3b与白塞病发病机制的关系
批准号:
14570241
负责人:
ISOGAI Hiroshi
金额:
$2.24万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2002
资助国家:
日本
项目状态:
已结题
起止时间:
2002 至 2003

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中文摘要
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英文摘要
About 1kb of Brn 3b DNA was obtained PCR from cDNA library of human embryonic brain. The product was inserted into Escherichia coli and the bacteria produced Brn 3b protein. The bacteria strain was agglutinated by anti-serum to synthetic peptide of Brn 3b. Furthermore, several sera from the patients with BD agglutinated this strain. The results suggested that the Brn 3b protein was correlated with the Behcet's disease.Now, it is the final stage for developing TG mice which were inserted this DNA.
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DOI: --
发表时间: 2003
期刊: Advances in Experimental Medicine and Biology(Kluwer Academic/Pleunum Publishers, New York) Vol 528
影响因子: --
作者: [Isogai E, Hirata M, Isogai H., Matuso K., Kimura K, Yokota K, Oguma K, Tojo M, Kaneko F, Kotake S, Ohno S]
通讯作者: Ohno S
Emiko Isogai: "Antibody cross reactivity from sera of patients with Behcet's disase with synthetic peptides that have homologies with proteins from Streptococcus sanguis"The Journal of Applied Research. 2(3). 185-191 (2002)
Emiko Isogai:“白塞病患者血清中的抗体与与血链球菌蛋白质具有同源性的合成肽发生交叉反应”应用研究杂志。
DOI: --
发表时间:
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作者: []
通讯作者:
E.Isogai: "Antibody Cross Reactivity From Sera of Patients With Behcet's Disease With Synthetic Peptides That Have Homologies With Proteins From Streptococcus sanguis"Journal of Applied Research. 2・3. 1-7 (2002)
E.Isogai:“白塞氏病患者血清与与血链球菌蛋白质具有同源性的合成肽的抗体交叉反应”应用研究杂志 1-7 (2002)。
DOI: --
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作者: []
通讯作者:
Antibody cross reactivity from sera of patients with Behcet's disease with synthetic peptides that have homologies with protein from Streptococcus sanguis.
白塞氏病患者血清中的抗体与与血链球菌蛋白具有同源性的合成肽发生交叉反应。
DOI: --
发表时间: 2002
期刊: J.Appl.Res. 2(3)
影响因子: --
作者: [Isogai E, Isogai H, Kotake S, Ohno S, I shihara M, Aoki K, Tojc M, Kaneko F, Yokota K, Oguma K]
通讯作者: Oguma K
9
    The approach of synthetic steroid ceragenin to curative medicine for infectious diseases
    • 批准号:
      22590397
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2010
    • 负责人:
      ISOGAI Hiroshi
    • 依托单位:
    Study of Helicobacter pylori infection using G-CSF transgenic mice.
    • 批准号:
      10670264
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.11万
    • 财政年份:
      1998
    • 负责人:
      ISOGAI Hiroshi
    • 依托单位:
    Experimental Study of Metastasis and Invasion Related Oncogene by Using Oral Cancer Cell Lines
    • 批准号:
      09672032
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.37万
    • 财政年份:
      1997
    • 负责人:
      ISOGAI Hiroshi
    • 依托单位:
    海外基金