The approach of synthetic steroid ceragenin to curative medicine for infectious diseases

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Ceragenin (CSA) is the antibacterial material which has a steroid ring. CSA covered and mixed to a dental material. It controlled to bacterial biofilm formation on those surfaces and inhibited the bacterial growth in liquid by exuding in culture solution. Moreover, a bacterial resistant was not induced, even if staphylococcus was cultivated repeatedly in low-concentration of CSA. CSA showed the antitumor activity by inducing apoptosis to cancer cells.