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The effects of prescription at high altitude training on health and disease in middle-aged and elderly obese men in aging society

高原训练处方对老龄化社会中老年肥胖男性健康与疾病的影响

基本信息

批准号：
16500459
负责人：
TERAO Tamotsu
金额：
$ 0.83万
依托单位：
Tokai University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2005
项目状态：
已结题

项目摘要

The effects of walking exercise in a hypobaric hypoxic environment on peripheral blood circulation and artery stiffness in middle-aged and elderly obese men was studied. In experiment 1, subjects were asked to rest for 20 minutes in two environments : a hypobaric hypoxic environment (HE) at 1500m simulated altitude and normobaric normoxic environment (NE) at sea level. Subjects walked for 60 minutes on a treadmill in three environments : HE1 (1500m), HE2 (2000m) and NE. In experiments 2 and 3, subjects exercised in HE (1500m) for 60 min/day, 2-3 days/week for 4 and 6 weeks. The ratio of d/a with accelerated plethysmogram (APG) wave and APG index at rest in HE were significantly higher than those in NE. The ratio of d/a and APG index at 60 minutes post-exercise in HE1 and HE2 were significantly higher than in NE. The ratio of b/a at 60 minutes post-exercise in HE 1 and HE2 was significantly lower than in NE. No significant differences were found in APG index, the ratio of b/a and d/a between H1 and H2. Areas of skin high temperature at 30 and 60 minutes post-exercise in HE showed a tendency larger than that in NE. The ratio of b/a after the training for 4 and 6 weeks was significantly lower than that before the training. The ratio of d/a and APG index after the training for 4 and 6 weeks were significantly higher than that before the training. The arterial stiffness index (baPWV) after the training for 6 weeks was significantly lower than that before the training. These results suggest that walking exercise in a hypobaric hypoxic environment may be a useful method for improvement of peripheral circulation and artery stiffness in middle aged and elderly men.

研究了低压低氧环境下步行锻炼对中老年肥胖男性外周血循环和动脉僵硬度的影响。实验1中，受试者被要求在两种环境中休息20分钟：在1500米模拟海拔的低压低氧环境（HE）和在海平面的常压常氧环境（NE）。受试者在三种环境中在跑步机上行走60分钟：HE 1（1500 m），HE 2（2000 m）和NE。实验2和实验3分别在HE（1500 m）中进行60 min/d的运动，每周2-3 d，连续4周和6周。HE组静息时APG波的d/a比值和APG指数均显著高于NE组。运动后60 min时，HE 1和HE 2的d/a比值和APG指数均显著高于NE。HE 1和HE 2运动后60 min的B/a比值显著低于NE。H1和H2的APG指数、B/a和d/a比值无显著性差异。运动后30、60 min HE组皮肤高温面积有大于NE组的趋势。训练4周和6周后B/a比值明显低于训练前。训练4周和6周后d/a比值和APG指数均显著高于训练前。训练6周后动脉僵硬度指数（baPWV）较训练前明显降低。这些结果表明，在低压低氧环境中步行锻炼可能是改善中老年人外周循环和动脉僵硬度的有效方法。