Differentiation of finger plethysmographical vector index to the vascular tone and blood pressure related components : a simple new measure of the cardiovascular reactivity type

手指体积描记矢量指数与血管张力和血压相关成分的区分：心血管反应类型的简单新测量

• 批准号: 16530473
• 负责人: TANAKA Gohichi
• 金额: $ 2.3万
• 依托单位: Sapporo Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2004
• 资助国家: 日本
• 起止时间: 2004 至 2006
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-16530473/
• 关键词: finger photoplethysmogram; finger vascular tone; finger arterial elasticity; endotherial function; mental stress; health assessment; 心理的影響要因; 血液容積; 血圧; 心拍出量; 総末梢血管抵抗反応

1.We defined a new vector index (VI) derived from finger photoplethysmogram and differentiated VI to the vascular tone and blood pressure related components. Under various mental stress conditions, VI revealed to be highly correlated with blood pressure and the orientation of VI seemed to be stable. Considering the complex calculation for estimating VI and its orientation, simple use of the normalized pulse volume (NPV ; Sawada et al., 2001) will be superior to VI.2.We advocated a new measure of the finger arterial elasticity derived from finger photoplethysmogram. Based on our exponential model of the pressure (P)-volume (V) relationship in the finger artery (V=a-b×exp(nP)), the parameter n is defined as finger arterial elasticity index (FEI). We developed a new estimating method for FEI, which were free from compliance and thus from blood pressure measurement. We applied to get patent by our noble estimation method.3.Ultrasonic imaging of the flow mediated-dilation (%FMD) in brachial artery is a confirmatory testing of human endotherial function. Kuvin et al. (2003) developed a peripheral arterial endotherial testing by finger photoplethysmogram (PWA). We improved PWA by applying NPV for flow mediated dilation of the finger artery and advocated finger arterial flow-mediated dilation ratio (FFMDR) as a simple measure of the endotherial function. Correlation between FFMDR and %FMD seemed to be reasonably high (r=0.67, n=35, young healthy male subjects).

1.我们定义了一种新的矢量指数（VI），并将其与血管张力和血压相关成分进行了区分。在各种精神应激条件下，VI显示出与血压高度相关，并且VI的取向似乎是稳定的。考虑到估算VI及其方向的复杂计算，简单使用归一化脉冲体积（NPV; Sawada et al., 2001）将优于VI.2。我们提出了一种新的测量手指动脉弹性的方法，该方法来源于手指光体积描记图。根据手指动脉压力(P)-体积(V)关系的指数模型（V=a-b×exp(nP)），将参数n定义为手指动脉弹性指数（FEI）。我们开发了一种新的估算FEI的方法，该方法不需要依从性，因此不需要测量血压。我们用高贵的估价法申请了专利。肱动脉血流介导扩张（%FMD）的超声成像是对人内皮功能的确证性检测。Kuvin等人（2003）开发了一种外周动脉内皮检测方法，即手指光容积描画法（PWA）。我们将NPV应用于手指动脉血流介导的扩张来改善PWA，并提倡手指动脉血流介导的扩张比（FFMDR）作为内皮功能的简单衡量指标。FFMDR与%FMD之间的相关性似乎相当高（r=0.67, n=35，年轻健康男性受试者）。

项目成果

Near infrared spectroscopy for monitoring flow-mediated dilation ofradial artery during reactive hyperemia : Correlati on study with thesystemic and finger arterial stiffness

近红外光谱监测反应性充血期间血流介导的桡动脉扩张:与全身和手指动脉僵硬度的相关性研究

• 发表时间: 2004
• 期刊: International Journal of Psychophysiology 54・1-2
• 作者: Tanaka;G.
• 通讯作者: G.

指動脈弾力性測定プログラム、指動脈弾力性測定装置および指動脈弾力性測定方法

数字动脉弹性测量程序、数字动脉弹性测量装置及手指动脉弹性测量方法

• 发表时间: 2007

Analysis of gender differences in correlation of brachial-ankle pulse wave velocity with body mass index and blood pressure in healthy youths

健康青年臂踝脉搏波速度与体重指数、血压相关性的性别差异分析

• 发表时间: 2005
• 期刊: Bulletin of School of Health Sciences Sapporo Medical University 8
• 作者: 奥野直;木村みさか 他2名;Horiguchi Masami
• 通讯作者: Horiguchi Masami

心臓血管系の簡易健康評価法 -容積脈波による指動脈弾力指数の提案-

一种简单的心血管系统健康评估方法-利用体积脉搏波的数字动脉弹性指数的提议-

• 发表时间: 2006
• 期刊: 生理心理学と精神生理学 24・2
• 作者: Tanaka;Gohichi;田中 豪一
• 通讯作者: 田中 豪一

Exponential model of pressure-volume relationship in the finger artery : Theoretical and experimental evaluation of vascular tone under mental stress and reactive hyperemia.

手指动脉压力-容量关系的指数模型：精神应激和反应性充血下血管张力的理论和实验评估。

• 发表时间: 2005
• 期刊: Advances in Psychology(Shohov S. editor.)(Nova Science Publisher) (New York) Vol.34
• 作者: Tanaka;G.
• 通讯作者: G.