Amediating role of allostatic load between chronic psychosocial stress and the vascular health in healthy young men

健康年轻男性慢性心理社会压力与血管健康之间的调节负荷的调节作用

• 批准号: 21300252
• 负责人: TANAKA Gohichi
• 金额: $ 5.99万
• 依托单位: Sapporo Medical University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21300252/
• 关键词: 心理社会的要因; 慢性ストレス; アロスタティック負荷; 動脈スティフネス; 心臓血管系; 生活習慣病; 食行動; 運動習慣; ストレス; 指動脈弾力指数

The present cross-sectional study was one part of a 5-years prospective cohort study which examines the effects of psychosocial and chronic stress on the early signs of cardiovascular disease in healthy young people. We examined especially if the association between psychosocial factors and vascular health was explained by allostatic load in healthy young men. Partial correlations controlling for age were significant for finger arterial stiffness with inflammatory markers, as well as with a cumulative allostatic load index(ALI). In addition, ALI was significantly correlated with angerrelated personality and lifestyle factors involving unhealthy eating habits and physical exercise. In conclusion, arterial stiffness in young people seems to be associated with vascular pro-inflammation as well as with overall physiological dysregulation and allostatic load. These associations would be moderated by eating lifestyle and psychosocial stress.

目前的横断面研究是一项为期5年的前瞻性队列研究的一部分，该研究探讨了心理社会和慢性压力对健康年轻人心血管疾病早期体征的影响。我们特别研究了心理社会因素和血管健康之间的关联是否可以用健康年轻男性的非稳态负荷来解释。控制了年龄的偏相关性对于手指动脉僵硬度与炎症标志物以及累积的非稳态负荷指数（ALI）是显著的。此外，ALI与愤怒相关的个性和生活方式因素（包括不健康的饮食习惯和体育锻炼）显著相关。总之，年轻人的动脉硬化似乎与血管促炎症以及整体生理失调和非稳态负荷有关。这些关联会受到饮食、生活方式和心理压力的影响。

项目成果

Gender differences in the relationship among eating behaviors, cardiovascular risk factors, anger expression, depression and anxiety in healthy young men and women

健康青年男女饮食行为、心血管危险因素、愤怒表达、抑郁和焦虑之间关系的性别差异

• 发表时间: 2009
• 作者: 高橋隆宜;山田冨美雄;森一彦; 宮野道雄;和気秀文;Yumiko NARA;Horiguchi M
• 通讯作者: Horiguchi M

Fish consumption and psychophysiological activities during mental stress

精神压力期间的鱼类消费和心理生理活动

• 发表时间: 2011
• 作者: Matsumura;Kenta
• 通讯作者: Kenta

ポジティブ性格特性はストレス回復機序を媒介として身体健康へ影響する.

积极的人格特质通过压力恢复机制影响身体健康。

• 发表时间: 2011
• 作者: 新岡正;大貫宗一郎;田中豪一
• 通讯作者: 田中豪一

Mean recovery rate : A simple measure ofrecovery uncontaminated by the carryover effect

平均回收率：不受残留效应污染的回收率的简单衡量标准

• DOI: 10.1111/j.1468-5884.2009.00410.x
• 发表时间: 2009
• 期刊: Jpn Psychol Res
• 影响因子: 0.8
• 作者: 佐藤幸治;家光素行;相澤勝治;目崎登;藤田聡;田中麻衣子;Sawada Y Kato Y
• 通讯作者: Sawada Y Kato Y

The association between chronic psychosocial stress, allostatic load, and vascular health in asymptomatic young men : A pilot study using a novel finger arterial stiffness index

无症状年轻男性慢性心理社会压力、稳态负荷和血管健康之间的关联：使用新型手指动脉僵硬度指数的初步研究

• DOI: 10.1111/j.1468-5884.2011.00461.x
• 发表时间: 2011
• 期刊: Jpn Psychol Res
• 影响因子: 0.8
• 作者: Tanana G;Kato Y;Matsumura K;Horiguchi M;Ogasawara H;Sawada Y
• 通讯作者: Sawada Y