Chemical Sensor and Biosensor based on carbon nanotube modified with molecular receptors

碳纳米管（CNTs）独特的电子、化学和机械性能使其在化学和生物化学传感器方面极具吸引力。碳纳米管具有快速的电子转移动力学和浓度函数，可作为生物传感器的优良传感器。低分子量酶如辣根过氧化物酶（HRP）和微过氧化物酶（MP-11）被物理吸附到碳纳米管电极上。结果表明，HRP基纳米管生物传感器对过氧化氢具有很高的灵敏度，而MP-11基纳米管生物传感器重复使用稳定性很好。此外，葡萄糖氧化酶共价键合到纳米管制备的葡萄糖传感器响应葡萄糖作为电化学介体的存在下，苯醌敏感。此外，冠醚、环糊精和环状多胺修饰的碳纳米管电极分别对邻苯二酚胺、双酚A和二碳酸类化合物具有灵敏的响应，并具有一定的浓度函数。

The unique electronic, chemical and mechanical properties of carbon nanotubes (CNTs) make them extremely attractive for chemical and biochemical sensors. Preliminary studies demonstrated that CNTs have fast electron-transfer kinetics and concentration function suggesting that they may serve as excellent transducers for biosensors.Low molecular weight enzymes such as horseradish peroxidase (HRP) and microperoxidase (MP-11) were physically adsorbed onto the nanotube electrode. As a result, HRP-based nanotube biosensor responded to hydrogen peroxide with high sensitivity, while MP-11-based nanotube biosensor was very stable for its repeated use. Also, glucose sensor prepared by covalent bonding of glucose oxidase into the nanotube responded sensitively to glucose in the presence of benzoquinone as an electrochemical mediator. Furthermore, nanotube electrodes modified with crown, cyclodextrine, and cyclic polyamine responded sensitively to catecholamine, bisphenol A, dicarbonic acid compounds, respectively, with some concentration functions based on the host-gest interactions.