Neural correlation between the central and the peripheral neurons in the regulation of the digestive tract in Aplysia

海兔消化道调节中枢和周围神经元的神经相关性

基本信息

  • 批准号:
    16570066
  • 负责人:
  • 金额:
    $ 1.86万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 财政年份:
    2004
  • 资助国家:
    日本
  • 起止时间:
    2004 至 2005
  • 项目状态:
    已结题

项目摘要

The enteric nervous system, containing a large number of peripheral neuronal somata, is intrinsic to the digestive organs in Aplysia. Two types of rhythmic bursting activities were recorded from the peripheral neurons in preparations in which the central nervous system had been removed. One of the bursting activities was shorter in duration and was recorded in synchrony from the neurons on the crop, the ring nerve and the gizzard. This activity was suggested to cause the neurogenic movement of the gizzard. The other bursting activity was longer in duration and was recorded synchronously from the neurons on the crop and the ring nerve, but not on the gizzard. When the crop, the organ in which food is temporarily stored, was distended by means of a small balloon, the frequencies of both types of bursting activities were increased. These results suggest that varoceptive peripheral reflexes are involved in the regulation of digestive movements in Aplysia, while the functions of the longer-duration bursting activity should be examined in future studies.The autonomic movements of the gizzard comprise both constrictions for trituration and the partial contractions for mixing its contents. It was shown that the constrictions are the neurogenic contractions originating in the synchronous bursting activities of peripheral neurons as described above and the partial contractions are the myogenic ones generated by the pacemaker potential in the musculature. Acetylcholine applied to the gizzard increased frequencies of both the synchronous bursting activities of the peripheral neurons and the pacemaker potentials in the muscle cells with a dose-dependent manner, while the synchrony among the peripheral bursting neurons was augmented. The results suggest that both the peripheral neurons and muscle cells on the gizzard have cholinergic receptors and are involved in the acceleration of digestive movements of the gizzard.
肠神经系统是消化器官固有的神经系统,含有大量的外周神经元胞体。两种类型的节律爆发活动记录从外周神经元的准备,其中中枢神经系统已被删除。其中一种爆发活动持续时间较短,并且是从作物,环神经和砂囊上的神经元同步记录的。这种活动被认为是导致砂囊神经性运动的原因。另一种爆发活动持续时间较长,并且从作物和环神经上的神经元同步记录,而不是在砂囊上。当作物,暂时储存食物的器官,通过一个小气球膨胀时,两种类型的爆裂活动的频率都增加了。这些结果表明,静脉曲张性外周反射参与了调节消化运动,而更长时间的爆发活动的功能,应在未来的研究中进行检查。自主运动的砂囊包括收缩的研磨和部分收缩的内容物的混合。结果表明,收缩是起源于上述外周神经元的同步爆发活动的神经性收缩,而部分收缩是由肌肉组织中的起搏电位产生的肌性收缩。乙酰胆碱作用于肌砂囊后,外周神经元同步爆发活动频率和肌细胞起搏电位频率均呈剂量依赖性增加,同时外周爆发神经元间的同步性增强。结果提示,肌细胞和周围神经元均具有胆碱能受体,参与肌细胞和周围神经元对肌细胞消化运动的加速作用。

项目成果

期刊论文数量(20)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Synchronous activities of peripheral neurons and their mechanoreceptive regulation in the enteric nervous system of Aplysia.i
海兔肠神经系统周围神经元的同步活动及其机械感受调节。i
Synchronous activities of neurons distributed throughout the neural plexus of the digenstive organ in Aplysia.
海兔消化器官神经丛中神经元的同步活动。
Excitatory neural control of posterograde heartbeat by the frontal ganglion in the last instar larva of a lepidopteran, Bombyx mori.
鳞翅目家蚕最后龄幼虫额叶神经节对后行心跳的兴奋性神经控制。
Gizzard movements in Aplysia are composed of both neurogenic contractions attributable to the peripheral neurons and myogenic contractions.
海兔的砂囊运动由周围神经元引起的神经源性收缩和肌源性收缩组成。
Dual acceleratory actions of acetylcholine on the autonomic movements of gizzard in Aplysia.
乙酰胆碱对海兔砂囊自主运动的双重加速作用。
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KUROKAWA Makoto其他文献

KUROKAWA Makoto的其他文献

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{{ truncateString('KUROKAWA Makoto', 18)}}的其他基金

Comparative physiology of morphology and function of the enteric nervous system.
肠神经系统形态和功能的比较生理学。
  • 批准号:
    21570080
  • 财政年份:
    2009
  • 资助金额:
    $ 1.86万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Peripheral neuronal mechanisms for control of the gill movements in Aplysia
控制海兔鳃运动的周围神经机制
  • 批准号:
    11168225
  • 财政年份:
    1999
  • 资助金额:
    $ 1.86万
  • 项目类别:
    Grant-in-Aid for Scientific Research on Priority Areas (A)

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Cellular and molecular characterization of the digestive tract sub-epithelium
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开发利用搭载复眼系统的内窥镜对消化道进行三维全景观察的技术。
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