Clinical basic research for the surgical treatment of the cervical carotid artery stenosis.

本研究的目的是探讨颈动脉狭窄的临床病理特点，特别是对动脉壁的特征、肝素辅因子Ⅱ和血小板聚集的病理意义等方面的研究，在2年的研究中，发现了以下4个新的研究领域：该期刊报道了重要的主题。1颈动脉分叉处动脉壁变化的特征性病理学发现：变化的关系弹性/这些发现为外科手术和血管内治疗策略提供了重要信息。2肝素辅因子II的生理和病理机制。3监测患者的血小板聚集和肝素活化在这些研究的基础上，我们继续研究颈动脉疾病的真实病理特征，并创造最适当的治疗选择和方法。

The purpose of this study is to approach clinical-pathological feature of the carotid artery stenosis, ; especially about the arterial wall characteristics, and pathological meaning of heparin cofactor II and platelet aagregation,.During 2 year research periods, the following four subjects were revealed as new evidence in this field, and important topics were reported in the journal.1 Characteristic pathological findings of the arterial wall changes at the carotid bifurcation : relationship of the changes the elastic/muscular artery and limitation of the atheroma plaque extention.These findings should reveal important information for surgical and endovascular treatment strategy.2 Physiological and pathological mechanisms of heparin cofactor II.3 Monitoring of platelet aggregation and heparin activation in patients undergoing neuroendovascular treatment or angiography.Based on these studies, we continued research to investigate true pathological features of the carotid artery disease and to create the most adequate treatment selection and methods.